Parents, siblings, and kids of people with celiac disease are at high risk of developing the disease, reports a study. The findings of the study are published in the journal Mayo Clinic Proceedings.
This study calls for screening of all first-degree relatives of patients not just those who show symptoms.
Gluten-Free Diet Followers on the Rise Among People Without Celiac Disease
Gluten-free diet is recommended for people with an autoimmune disorder called celiac disease. But people without the disease also go gluten-free claims a study.
Advertisement
‘First-degree relatives of celiac disease patients carry a 1-in-10 chance of developing the disease,’
Read More..
Tweet it Now
Read More..
The retrospective study found that 44% of screened first-degree relatives had celiac disease. Of those patients, 94% had symptoms that were not classic or had no symptoms at all.
"Research has shown that family members of celiac disease patients are at higher risk, and we used our Mayo Clinic data to show that proactive screening of first-degree relatives, regardless of whether they showed symptoms, resulted in diagnoses that would have been missed," says Imad Absah, M.D., a Mayo Clinic pediatric gastroenterologist and the study's lead author.
![Multiple Sclerosis Patients Present With High Incidence of Celiac Disease]( "Multiple Sclerosis Patients Present With High Incidence of Celiac Disease")
In a recent study, researchers analyzed the prevalence of celiac disease in Multiple sclerosis (MS) patients and their first-degree relatives.
Celiac disease is an immune reaction to eating gluten, a protein found in wheat, rye, and barley, that can damage the lining of the small intestine over time. This can lead to malabsorption of nutrients, and cause diarrhea, fatigue, weight loss, and other complications. There's no cure for celiac disease, but patients can manage symptoms with a strict gluten-free diet.
The study looked at a retrospective sample of 104 patients diagnosed with celiac disease between 1983 and 2017, based on Mayo Clinic records and celiac disease registry data. Researchers then identified 477 first-degree relatives, of whom 360 were screened for celiac disease. Of those, 160 were diagnosed with celiac disease. The median period between diagnosis of the initial patient and the relative was just under six months.
More screening for celiac disease among family members could prevent long-term complications, such as nutritional deficiencies, development of new autoimmune conditions, and small bowel malignancy, according to the Mayo Clinic study. Other studies also have shown a higher prevalence of the celiac disease in family members.
"Gastroenterologists and general practitioners should ask about any family history of celiac disease among their patients' parents, siblings, and children. And if they're present during the clinic visit, they should offer screening," says Dr. Absah.
Regarding screening, Joseph Murray, M.D., a Mayo Clinic gastroenterologist, and co-author, says that patients should not change their diet to avoid foods containing gluten before testing.
"This research illustrates why it is important for clinicians and patients to be vigilant for celiac disease, especially in those with a family history," Dr. Murray says.
Source: Eurekalert
Multiple Sclerosis Patients Present With High Incidence of Celiac Disease
In a recent study, researchers analyzed the prevalence of celiac disease in Multiple sclerosis (MS) patients and their first-degree relatives.
Advertisement
Celiac disease is an immune reaction to eating gluten, a protein found in wheat, rye, and barley, that can damage the lining of the small intestine over time. This can lead to malabsorption of nutrients, and cause diarrhea, fatigue, weight loss, and other complications. There's no cure for celiac disease, but patients can manage symptoms with a strict gluten-free diet.
The study looked at a retrospective sample of 104 patients diagnosed with celiac disease between 1983 and 2017, based on Mayo Clinic records and celiac disease registry data. Researchers then identified 477 first-degree relatives, of whom 360 were screened for celiac disease. Of those, 160 were diagnosed with celiac disease. The median period between diagnosis of the initial patient and the relative was just under six months.
More screening for celiac disease among family members could prevent long-term complications, such as nutritional deficiencies, development of new autoimmune conditions, and small bowel malignancy, according to the Mayo Clinic study. Other studies also have shown a higher prevalence of the celiac disease in family members.
"Gastroenterologists and general practitioners should ask about any family history of celiac disease among their patients' parents, siblings, and children. And if they're present during the clinic visit, they should offer screening," says Dr. Absah.
Regarding screening, Joseph Murray, M.D., a Mayo Clinic gastroenterologist, and co-author, says that patients should not change their diet to avoid foods containing gluten before testing.
"This research illustrates why it is important for clinicians and patients to be vigilant for celiac disease, especially in those with a family history," Dr. Murray says.
Source: Eurekalert
Gluten Consumption in Childhood Linked to Celiac Disease Risk
In children, for every 1-gram per day increase in gluten consumption there was an associated higher risk of celiac disease and celiac disease autoimmunity, found new research.
Advertisement
 Too Much Gluten in Your Child's Diet May Up Celiac Disease RiskEating a gluten-rich diet can put your child at a higher risk of developing celiac disease, reveals a new study. | Advertisement
|
Advertisement
Recommended Readings
Latest Research News
Diagnosed autistic individuals showed increased premature mortality in the UK, highlighting urgent needs to address associated inequalities.
Study reveals a correlation between hearing impairment and distinct brain region variances, contributing to dementia.
Financial impact of caring for individuals with neurodegenerative disorders reaches hundreds of billions annually in the United States.
Experts emphasize that addressing the skills gap demands immediate attention and innovative solutions, including education, re-training, and significant time investment.
New study unveiled the cells' ability to adapt in responses and potential implications for conditions such as diabetes and cancer.