About Careers MedBlog Contact us

New Saliva Test Can Help Detect Alzheimer's Disease

by Adeline Dorcas on December 14, 2018 at 11:07 AM
Font : A-A+

New Saliva Test Can Help Detect Alzheimer's Disease

Newly developed saliva test can now help in detecting Alzheimer's disease and mild cognitive impairment, reports a new study.

Scientists have identified biomarkers that can help in early detection of mild cognitive impairment and Alzheimer's disease in saliva samples.


A saliva test would prove useful in clinical settings for its ease and non-invasive nature. It also has the potential to detect neurodegenerative diseases earlier on, allowing for early intervention, said a team from the University of Alberta in Canada.

Liang Li, Professor in the Department of Chemistry, and Roger Dixon, Professor in the Department of Psychology examined saliva samples from three sets of patients -- those with Alzheimer's disease, those with mild cognitive impairment and those with normal cognition.

Using a powerful mass spectrometer, the team examined more than 6,000 metabolites -- compounds that are part of our body's metabolic processes -- to identify any changes or signatures between groups.

"In this analysis, we found three metabolites that can be used to differentiate between these three groups," said Li.

"This is preliminary work because we've used a very small sample size. But the results are very promising. If we can use a larger set of samples, we can validate our findings and develop a saliva test of Alzheimer's disease," Li noted.

In addition, identifying these biomarkers is the ability to conduct efficacy testing for treatments.

"Using the biomarkers we can also do testing to see what types of treatments are most effective in treating Alzheimer's disease, from diet to physical activity to pharmaceuticals," added Li.

"So far, no disease-altering interventions for Alzheimer's disease have been successful," said Dixon. "For this reason, researchers are aiming to discover the earliest signals of the disease so that prevention protocols can be implemented."

Source: IANS


Recommended Reading

Latest Research News

 New Insights into How the Immune System Responds to Spinal-Cord Injuries
New study findings delineate how aging affects the immune response following Spinal cord injury (SCI) and highlight the participation of the spinal cord meninges in repair.
Nearsightedness: Atropine Eye Drops may Slow Progression in Kids
A recent clinical trial suggests that the first medication therapy to reduce the progression of nearsightedness in children could be on the way.
Autoimmune Diseases Affect One in Ten: Study
Autoimmune disorders were found to be linked to Sjogren's, systemic lupus erythematosus, and systemic sclerosis.
Remarkable Journey of Transforming Lives With Brain Pacemaker
Successful brain pacemaker implantation has helped a 51year old Parkinson's disease patient to revitalize her quality of life.
What Are the Effects of Healthy Lifestyle on Osteoarthritis?
Recent recommendations on lifestyle behaviors to prevent progression of rheumatic and musculoskeletal diseases revealed.
View All
This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close

New Saliva Test Can Help Detect Alzheimer's Disease Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests