The age-specific probabilities of live birth after in vitro fertilization (IVF) with frozen eggs have been codified for the first time by researchers from New York Medical College and the University of California Davis.
A team of researchers led by Kutluk Oktay, M.D., a New York Medical College physician/scientist who specializes in preserving the fertility of female cancer patients, conducted a meta-analysis of oocyte cryopreservation cycles using individualized patient data to report the probability of live-birth from IVF cycles.
The study, "Age-specific probability of live birth with oocyte cryopreservation: an individual patient data meta-analysis," was published in the online May issue of the American Society for Reproductive Medicine's journal Fertility and Sterility.
"Because of this breakthrough, women and fertility doctors will now be able to use a live pregnancy rate estimator to calculate their individual chances and to make a well-informed decision about the procedure," said Dr. Oktay.
The study also showed that while egg freezing success rates decline with age as expected, there is a sharper drop after age 36. Though pregnancies can result from frozen eggs implanted as late as age 44, the success rates are less promising after age 42.