Lowering high blood pressure, reducing salt intake, and eliminating trans fat from diet could help prevent 94 million early deaths around the world, according to a new study led by Harvard T.H. Chan School of Public Health.
"Focusing our resources on the combination of these three interventions can have a huge potential impact on cardiovascular health through 2040," said lead author Goodarz Danaei, associate professor of global health at Harvard Chan School.
The study will be published in the journal Circulation.
They estimated that scaling up treatment of high blood pressure to 70% of the world's population could extend the lives of 39.4 million people. Cutting sodium intake by 30% could stave off another 40 million deaths and could also help decrease high blood pressure, a major risk factor for CVD. And eliminating trans fat could prevent 14.8 million early deaths.
Regions expected to benefit most from the interventions include East Asia, the Pacific, and South Asia, as well as countries in sub-Saharan Africa.
The authors said that a variety of programs and policies would be necessary to reduce premature CVD-related deaths. One important strategy would be to increase the use of blood pressure medications, many of which are safe and affordable.
The researchers acknowledged that scaling up the three interventions would be a "huge challenge," requiring countries to commit additional resources to boost health care capacity and quality. But they added that previous analyses have shown that the interventions are achievable and affordable. For example, a Kaiser Permanente program in Northern California increased control of hypertension to 90% among thousands of the health system's patients between 2001 and 2013, using strategies such as improved treatment protocols, patient-friendly services, and healthcare information systems that facilitate tracking people with hypertension. Similar approaches have been adapted and tested in some low- and middle-income countries, leading to notable improvements in hypertension treatment and control, the authors said.
"These are realistic goals that have been shown to be attainable on smaller scales," said Danaei. "We need the commitment to scale up the programs to achieve them globally."