About Careers MedBlog Contact us

New Powerful Pain Relief Option With Sea Snail Venom

by Tanya Thomas on June 18, 2010 at 11:06 AM
Font : A-A+

 New Powerful Pain Relief Option With Sea Snail Venom

A pill for nerve-related pain which uses sea snail venom, developed by scientists, may prove to be 100 times as potent as other leading treatments.

Current medications for neurapathic disorders include morphine, which is highly addictive, and gabapentin - both act on nerve receptors. Sea snail venom, however, contains peptides called conotoxins, which act as an effective analgesic in mammals.


The only conotoxin-derived drug approved for human use is ziconotide. Unfortunately, the drug is susceptible to breakdown by enzymes in the saliva and gut, so it is administered by a pump surgically inserted into the abdominal wall, making it an invasive and expensive treatment.

According to New Scientist, Craik's team tested the conotoxin in rats with neuropathic pain. They found that a single oral dose significantly reduced pain using a standard test - how much pressure the rat could withstand before withdrawing its paw. Compared with gabapentin, conotoxin was judged to be 100 times more potent.

Because of the drug's potency, only very small doses are needed, reducing the risk of side effects, says Craik. The drug is awating approval from the US Food and Drug Administration for a trial in humans.

Source: ANI

Recommended Reading

This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close

New Powerful Pain Relief Option With Sea Snail Venom Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests