New Nanogel treatment for systemic lupus erythematosus, a disease attacking healthy tissues of the body, leading to inflammation and tissue damage. Current treatments are focused on suppression of the immune system, but these therapies can leave patients vulnerable to infection.
In this issue of the Journal of Clinical Investigation, Tarek Fahmy and colleagues at Yale University report the development of a nanogel-based delivery system that targets an immunosuppressive drug (mycophenolic acid) directly to tissues associated with immune cells.
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A nanogel is composed of a polymer containing pores that can be loaded with drug compounds. Fahmy and colleagues tested the mycophenolic acid-loaded nanogel in a mouse model of lupus. Mice treated with the nanogel lived longer than untreated mice or mice treated with mycophenolic acid alone. Additionally, the onset of kidney damage, a common complication of lupus, was delayed in nanogel-treated mice. These studies suggest that nanogel-based therapies may be useful in the treatment of SLE.
Source: Eurekalert
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A new research has found that lupus drugs do not raise cancer risk in patients.
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 Scientists Explore Link Between Lupus and Increased Risk of PreeclampsiaWomen with systemic lupus erythematosus have a higher risk of preeclampsia — a dangerous condition in which pregnant women develop high blood pressure and protein in their urine. | Advertisement
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Link Between Uranium Exposure and Increased Lupus Rate Identified
People who live near an uranium ore experience a higher rate of lupus, finds study conducted by scientists at the University of Cincinnati and Cincinnati Children's Hospital Medical Center.
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