About Careers Internship MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

New Memory Test Uncovers How Parkinson's Disease Can Alter Patient's Ability To Learn From Rewards

by Aruna on July 4, 2009 at 9:02 AM
Font : A-A+

New Memory Test Uncovers How Parkinson's Disease Can Alter Patient's Ability To Learn From Rewards

Scientists have developed a new neuropsychological memory test that could uncover how Parkinson's disease can alter people's ability to learn about the consequences of the choices they make.

Using the novel feedback-learning task on patients in Hungary, Dr. Mark Gluck at Rutgers' research team found that non-medicated patients in the early stages of Parkinson's were selectively impaired at learning from reward.

Advertisement

"What we are seeing in recently diagnosed patients is that prior to being put on any medications, they exhibit a selective impairment in their ability to learn from positive (rewarding) outcomes while their sensitivity to learning from negative (or punishing) outcomes is normal," said Gluck.

The researchers at Rutgers University, Newark, observed that the reward-learning deficit in un-medicated Parkinson's patients is quite opposite to that in patients who begin treatment with dopamine agonists-a standard therapy for treating the disease's motor symptoms.
Advertisement

On dopamine agonists, a patient's ability to learn from positive rewarding outcomes improved to normal levels, but their ability to learn from negative (or punishing) outcomes, which had previously been normal, was now impaired.

Gluck said that an increased sensitivity to learning from events that results in positive outcomes, coupled with a decrease in the ability to learn from negative outcomes, could explain why some Parkinson patients treated with dopamine agonists develop impulse-control disorders, including pathological gambling, hypersexuality, alcoholism, and compulsive eating and shopping.

Such behaviors can be understood as reward-seeking behaviors in the absence of appropriate sensitivity to their negative consequences.

The ability to test the effects on feedback learning in early onset Parkinson's disease could provide additional insight into the impact of dopamine loss on cognition and behavior.

It also could pave the way for identifying which Parkinson's patients are most likely to experience agonist-related feedback problems so they can be treated with alternate medications.

The findings of the study have been published in the journal Brain.

Source: ANI
ARU
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
Anemia among Indian Women and Children Remains a Cause of Concern- National Family Health Survey-5
H1N1 Influenza Prevention in Children: What Parents Need to Know
Dietary Factors Responsible for Dihydrotestosterone (DHT) Production and Hair Loss
View all
Recommended Reading
News Archive
Date
Category
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Varicocele Brain Exercises to Improve Memory Nutritional Management of Parkinsons disease Foods to Improve Memory Power Ways to Improve your Intelligence Quotient (IQ) Quick and Easy Ways to Memorize Things 7 Ways How Writing by Hand Improves Brain Power Mini-Mental Scale (Cognitive Function Test) 

Most Popular on Medindia

Loram (2 mg) (Lorazepam) Indian Medical Journals A-Z Drug Brands in India Pregnancy Confirmation Calculator Find a Hospital Blood - Sugar Chart Blood Donation - Recipients Drug - Food Interactions Drug Side Effects Calculator Calculate Ideal Weight for Infants
This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use
open close
ASK A DOCTOR ONLINE

×

New Memory Test Uncovers How Parkinson's Disease Can Alter Patient's Ability To Learn From Rewards Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests