Migraine is a recurrent throbbing headache that typically affects one side of the head and is often accompanied by nausea and disturbed vision. Sufferers of may soon find relief from migraine headaches as a new class of drugs is in the works to cure the pain. The medications would prevent migraine headaches before they start. They work to inhibit release of CGRP that is found to be elevated during migraine headache attacks and returns to normal when headaches are resolved.
Professor Thomas Ward at Dartmouth in New Hampshire said, "It would be highly effective for people who have not had effective treatment. Researchers say medications that block CGRP entirely could have a negative impact on the body's organs. The new class of drugs use monoclonal antibodies to target CGRP release that causes blood vessels to dilate and become inflamed."
Alder Pharmaceuticals, Amgen, Eli Lilly and Company, and Teva Pharmaceuticals are in the process of testing these new drugs that could bring relief for a substantial number of migraine headache sufferers with minimal side effects.