The innovative lab test developed helps explain why smaller multiparticulates eased the travel of drug from the mouth into the throat and body, reducing mouth residue, stated new study published by the European Journal of Pharmaceutical Sciences.
The new test let scientists easily screen different compositions of the carrier liquid and concentration of the particulates, in order to make swallowing as easy as possible.
Drug-Induced Birth Defects
Birth defects are abnormalities of function, structure or metabolism that are present since birth. Taking certain drugs during pregnancy can cause birth defects.
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‘The availability of predictive models to characterise the promising formulation platforms early during medicine development is key to producing medicines that are easier to take for patients with different swallowing capabilities. ’
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Dr Marco Ramaioli, Senior Lecturer at the University of Surrey and co-author of the study, said: "Many young children and older people find conventional tablets hard to swallow - making it difficult for them to complete drug therapy. We hope that this in vitro method, together with sensory tests, will help to develop novel medicines that could improve the lives of many people across the world."
Professor Catherine Tuleu from UCL School of Pharmacy commented: "It is exciting to see advancements in age appropriate medicine design such as multiparticulate systems but successful therapeutic outcomes rely on the development of appropriate administration vehicles."
Source: Eurekalert
Source: Eurekalert
What you Should Know About Drugs
Drugs, be it natural or synthetic have an effect on the body. Sometimes, they have more than one use. Two or more drugs taken together can have either positive or negative results. This is why, healthcare professionals need to provide adequate information on drugs and drug therapy for patients and caregivers to manage the illness. This ensures a safe, optimum and effective drug therapy, leading to
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 Drug Interaction CheckerDrug interactions checker can be used to check over the counter ( OTC) and regular prescription drugs interaction that can cause any unexpected health problems that can be harmful but generally not dangerous to you. | Advertisement
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Novel Group of Drugs to Treat Ovarian Cancer
New group of drugs, called PARG inhibitors, can kill ovarian cancer cells by targeting weaknesses within their ability to copy their DNA.
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