New Target May Help in Drug Discovery for Chronic Inflammatory Diseases
Newly identified target may help in the discovery of new treatments for chronic inflammatory diseases such as osteoarthritis, Alzheimer's disease, Parkinson's disease and lung cancer.
Newly identified target may help in the discovery of new treatments for chronic inflammatory diseases such as osteoarthritis, Alzheimer's disease, Parkinson's disease and lung cancer.
‘New study analyzes human T cell function under inflammatory conditions. The study examined T cells, which protect against bacteria, fungi, and viruses on mucosal surfaces. When activated against harmless substances, T cells may produce autoimmune diseases. The findings show that the set of genes expressed by T cells under pro-inflammatory conditions include several G-protein-coupled receptors (GPRs).’
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"We were encouraged to find that one of these targets, named GPR68, regulates the ability of T cells to produce chemical messengers. This may have implications for diseases on mucosal surfaces such as the lungs and gastrointestinal tract."The study examined T cells, which protect against bacteria, fungi, and viruses on mucosal surfaces. When activated against harmless substances, T cells may provoke autoimmune diseases.
Findings reveal that the set of genes expressed by T cells under pro-inflammatory conditions include several G-protein-coupled receptors (GPRs). Future studies will explore if blocking the GPR68 pathway can be a potential therapy for chronic inflammatory diseases.
New Understanding About Chronic Inflammatory Diseases
A novel way of how cells tune in to different inflammatory signals to understand what is happening in the body has been described by researchers.
A novel way of how cells tune in to different inflammatory signals to understand what is happening in the body has been described by researchers.
Age-Related Inflammation Cause Found
Immunosenescence is a process of deterioration of immune system with aging, in animals and humans. This process is found to be linked to systemic inflammation and many cancers.
Immunosenescence is a process of deterioration of immune system with aging, in animals and humans. This process is found to be linked to systemic inflammation and many cancers.
Potential New Treatments Uncovered for Inflammatory Diseases
In a latest study, an investigation was made of the links between 41 different cytokines and growth factors and 10.7 million DNA variations.
In a latest study, an investigation was made of the links between 41 different cytokines and growth factors and 10.7 million DNA variations.
