About Careers MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

New Blood Biomarker to Detect Autism

by Julia Samuel on May 4, 2016 at 10:54 PM
Font : A-A+

New Blood Biomarker to Detect Autism

A blood biomarker that may aid in earlier diagnosis of children with autism spectrum disorder (ASD)has been identified by researchers at UT Southwestern Medical Center.

Early intervention is the key to the best treatment for ASD, which affects about 1 in 70 children. Unfortunately, most children are not diagnosed until about age 4, when communication and social disabilities become apparent. This neurodevelopmental disorder is characterized by social interaction and communication challenges, and restricted and repetitive patterns of behavior.

Advertisement


In a recent edition of Scientific Reports, UT Southwestern researchers reported on the identification of a blood biomarker that could distinguish the majority of ASD study participants versus a control group of similar age range. In addition, the biomarker was significantly correlated with the level of communication impairment, suggesting that the blood test may give insight into ASD severity.

Dr. Dwight German, study senior author and Professor of Psychiatry at UT Southwestern. "The blood biomarker reported here along with others we are testing can represent a useful test with over 80 percent accuracy in identifying ASD."
Advertisement

Since other studies have found abnormalities in the immune systems of autistic children, researchers set out to search for antibodies in the blood related to ASD. In this study, researchers found that boys with ASD had significantly reduced levels of a serum IgG1 antibody.

Investigating further, researchers analyzed 25 peptoid compounds that bound to IgG1 and zeroed in on one - ASD1 - that was 66 percent accurate in diagnosing ASD. When combined with thyroid stimulating hormone level measurements, the ASD1-binding biomarker was 73 percent accurate at diagnosis.

More testing, including analysis of blood samples from girls with ASD, is needed to further validate the findings, Dr. German said. Girls made up a small ratio of the study group, and the biomarker did not correlate as strongly with ASD diagnosis as with boys.



Source: Newswise
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
World Disability Day 2022 - The Role of Innovative Transformation
Diet and Oral Health: The Sugary Connection May Become Sour
World AIDS Day 2022 - Equalize!
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Autism Thalassemia Rett Syndrome Acquired Epileptiform Aphasia Blood in Stools - Symptom Evaluation Bombay Blood Group 

Most Popular on Medindia

Indian Medical Journals Selfie Addiction Calculator Noscaphene (Noscapine) Post-Nasal Drip Loram (2 mg) (Lorazepam) Blood Pressure Calculator Find a Hospital Find a Doctor Sanatogen Accident and Trauma Care
This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close
×

New Blood Biomarker to Detect Autism Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests