Treating out-of-control blood pressure with antihypertensive medication can greatly reduce your risk for heart attack, stroke and heart failure, reveals a new study, but the current approach to treatment can't undo all of the previous damage or restore cardiovascular disease risk to ideal levels.
The Northwestern Medicine study sought to determine whether effective treatment of hypertension could lower the risk of cardiovascular disease to that seen in people who have always had ideal blood pressure levels. The best outcomes were seen in those who always had ideal levels of blood pressure and never required medications, said senior author Donald Lloyd-Jones, adding that those who were treated with medication and achieved ideal levels were still at roughly twice the risk of those with untreated ideal levels.
And, of course, people with untreated or uncontrolled high blood pressure were at even greater risk. He stressed that it remains very important to treat high blood pressure and that lowering blood pressure with antihypertensive medications has been found to lower the risk of cardiovascular disease significantly in middle-aged and older adults.
Results from the CARDIA participants indicate that middle-aged adults with blood pressure well-controlled by medication had longer exposure to higher blood pressure levels throughout young adulthood than those with ideal blood pressure without medication. As a result, they had significantly higher risk of end-organ damage, as measured by left ventricular mass, kidney function, and the presence of coronary artery calcification.
Future studies are still needed to investigate whether earlier treatment with medications could abolish excess cardiovascular disease risk found in this study, according to the authors. The study is published in the Journal of the American Heart Association.