About Careers MedBlog Contact us

Need to Standardize the Method for Measurement of Cigarette Smoke Constituents

by Dr. Trupti Shirole on February 14, 2015 at 5:31 PM
Font : A-A+

 Need to Standardize the Method for Measurement of Cigarette Smoke Constituents

Proposals to regulate cigarette smoke constituents such as tar, nicotine and carbon monoxide will only be possible if the methods used to measure them are consistent globally and are coordinated by an international body such as the International Organization for Standardization (ISO), recommended Christopher Wright, the head of Analytical Science at British American Tobacco.

Measuring cigarette smoke constituents in a reproducible and comparable manner has been a significant technical challenge due to their relatively low levels and the chemical complexity of smoke. This has been further complicated by the fact that historically test methods were developed in isolation, which has resulted in divergent or inconsistent techniques.


A group of World Health Organization (WHO) laboratories is currently conducting a validation exercise to establish methods to measure a specific set of nine smoke constituents, a process that would be of greater benefit if it was inclusive and open to peer review. Wright said, "Without collective investment in the development of robust quality control processes, technical agreement between industry, commercial testing laboratories and regulatory organizations will be very difficult to demonstrate, and perhaps impossible."

The US Food and Drug Administration (FDA) operate under an open and inclusive approach. It has recently implemented an initiative to establish reference products and proficiency studies, both fundamental requirements to establish 'fit-for-purpose' methods. This effort is a significant opportunity to harmonize analytical methods and improve their reproducibility to standards suitable for gathering regulatory data.

Wright said, "Regulatory authorities need to consider the reality of regulating cigarettes without harmonized quality control processes and comparable laboratory test data."

Source: Medindia


Recommended Reading

Latest General Health News

More Than 300 People on Texas-Mexico Cruise Ship Fall Sick
Over 300 people had fallen sick with illness caused by Norovirus on a US cruise ship, say authorities.
 No Smoking Day 2023: Ex-smokers in Wakefield Lead the Campaign
Ex-smokers in Wakefield have shared their stories to encourage others to give up cigarettes on No Smoking Day 2023 which falls on 8th March.
New Protein Linked to Neurodegeneration
Total levels of m6A in the nervous system rise with age and that (some) neurodegenerative diseases are characterized by RNA hypermethylation.
How Stress Disrupts Maturation of Brain's Reward Circuits?
New study provides insights into the impact of early-life adversity on brain development and on control of reward behaviors that underlie emotional disorders
 Indonesia Partners With FIND for Diagnostic Testing Access Initiative
Ministry of Health of the Republic of Indonesia signed a formal memorandum of understanding (MOU) that will expand access to essential diagnostics in the country.
View All
This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close

Need to Standardize the Method for Measurement of Cigarette Smoke Constituents Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests