Can human breast milk lower intestinal injury following a bone marrow transplant (BMT)? Yes, mother's milk was associated with decreased markers of intestinal inflammation and could be a valuable adjunct for patients after BMT.
Importance of Breast Feeding-Stages-Advantages-Benefits-Storage-FAQs
From antibodies, to the exclusive nutrients, the benefits of breastfeeding are incalculable.
From antibodies, to the exclusive nutrients, the benefits of breastfeeding are incalculable.
‘Administration of mother's milk resulted in decreased markers of intestinal inflammation and could be a valuable supplement for patients after bone marrow transplant (BMT).’
The results, indicating that human milk was associated with decreased markers of inflammation and injury in the stool, are reported in an article published in Breastfeeding Medicine, the official journal of the Academy of Breastfeeding Medicine published by Mary Ann Liebert, Inc., publishers. The high doses of chemotherapy and radiation administered before BMT initiate a cascade of events - including the release of cytokines such as interferons and interleukins - that can damage the lining of the intestines and alter the make-up of the intestinal microbiome. These and other changes involving T-cell activation can lead to the early stages of graft-versus-host-disease.
Pooja Khandelwal, MD, and coauthors from Cincinnati Children's Hospital Medical Center (OH) and Prolacta Bioscience (Duarte, CA) designed a study in which the children undergoing BMT receiving human milk or formula beginning three days before and continuing for two weeks after the procedure.
Bone Marrow Transplantation - Types - Procedure - Indications - Complications
Preferred Term is Hematopoietic stem cell transplantation. In this stem cell from bone marrow are injected into a recipient after treating them with growth factor.
Preferred Term is Hematopoietic stem cell transplantation. In this stem cell from bone marrow are injected into a recipient after treating them with growth factor.
"While only a pilot study, it has the potential of being a stimulus for proper prospective randomized studies that will explore the value of human milk as adjuvant therapy in the management of all transplants," says Arthur I. Eidelman, MD, Editor-in-Chief of Breastfeeding Medicine.
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