More Antibiotic-resistant Infections Seen in AIDS-immunocompromised Populations

by Mohamed Fathima S on  March 27, 2019 at 7:40 PM AIDS/HIV News
RSS Email Print This Page Comment bookmark
Font : A-A+

The emergence of antibiotic-resistant bacterial infections is seen more likely in populations with a high prevalence of AIDS-immunocompromised people, reveals new research. The study is published in the journal PLOS One.
More Antibiotic-resistant Infections Seen in AIDS-immunocompromised Populations
More Antibiotic-resistant Infections Seen in AIDS-immunocompromised Populations

"People with weakened immune systems are more vulnerable to opportunistic bacterial infections and are therefore frequently prescribed antibiotics to prevent or treat these infections," said Nina Fefferman, a professor in UT's Department of Ecology and Evolutionary Biology and coauthor of the study. "This increases the exposure of those bacteria to antibiotics, giving them more chances to evolve to become resistant to the medication and contributing to the current serious public health threat of drug-resistant diseases."

The research was led by Ashley DeNegre, who at the time of the study was an ecology and evolutionary biology PhD student at Rutgers University-New Brunswick. Kellen Myers, research assistant in UT's Department of Ecology and Evolutionary Biology and the UT-based National Institute of Mathematical and Biological Synthesis, also participated in the research.

For the study, scientists used mathematical models to integrate and extend results from many previous studies to consider the effect on the emergence of antibiotic resistance in two populations: the African nation of Swaziland, where there was a reported HIV/AIDS prevalence of 27.4 percent of the population, and Indonesia, in southeast Asia, where there was a much lower reported HIV/AIDS prevalence of 0.46 percent.

The results provide a better understanding of epidemiological patterns in populations with a high number of immunocompromised people due to AIDS and HIV, with special attention to low-income communities in the developing world.

"This work will hopefully help inform public health decision makers about how antibiotic stewardship should be tailored differently in high-prevalence AIDS-affected communities to help combat the rising global risk of drug-resistant infections," said Fefferman.



Source: Eurekalert

Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
Notify me when reply is posted
I agree to the terms and conditions
Advertisement

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Find a Doctor

Stay Connected

  • Available on the Android Market
  • Available on the App Store

News Category

News Archive