While primary biliary cirrhosis, a rare form of cirrhosis that destroys small bile ducts in the liver, usually affects young and middle-aged white women, minorities with the disease often have a more severe form than whites, according to a study published in the September issue of Hepatology, Reuters reports.
For the report, Marion Peters of the University of California-San Francisco and colleagues analyzed 535 individuals with PBC who were being screened for a clinical trial. Participants included 462 whites, 21 blacks, 42 Hispanics and 10 other minorities.
Researchers found that 46.6% of minorities were deemed ineligible for the trial because of greater disease severity, compared with 25.1% of whites. Blacks and Hispanics also were more likely than whites to have a lower activity level; severe or difficult-to-control chronic itching; and a more advanced form of the disease.
Source: Kaiser Family Foundation