About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

MicroRNA That Controls Blood Vessel Development Identified

by Rajashri on August 12, 2008 at 5:50 PM
Font : A-A+

 MicroRNA That Controls Blood Vessel Development Identified

A key regulatory factor that controls development of the human vascular system-the extensive network of arteries, veins, and capillaries that allow blood to reach all tissues and organs has been identified by an Indian-origin researcher.

Dr. Deepak Srivastava, the Director of the Gladstone Institute of Cardiovascular Disease (GICD), says that this advancement by researchers from the Gladstone Institute of Cardiovascular Disease (GICD) and UCSF attains significance because it may offer clues to potential therapeutic targets for diseases like heart disease or cancer, which are impacted by or affect the vascular system.

Advertisement

Working with colleagues from the University of California, San Francisco (UCSF), he has discovered that microRNA (miR-126), a tiny RNA molecule, is intimately involved in the response of blood vessels to angiogenic signals.

A research article in the journal Developmental Cell describes Angiogenesis as the process of vascular development.

A cascade of genes orchestrate a series of events leading to formation of blood vessels in an embryo.
Advertisement

"Some of these same gene regulatory networks are re-activated in the adult to direct the growth of new blood vessels. This can be beneficial, as in the case of a heart attack," said Dr. Jason Fish, lead author of the study.

The researcher further said that blood vessel formation could also contribute to disease in settings like cancer, where vessels feed a growing tumour.

"Finding that a single factor regulates a large part of the angiogenic process creates a significant target for therapeutic development for any disease involving the vascular system," said Dr. Srivastava.

"The next step is to find ways to modify this microRNA in the setting of disease and test its ability to alter the disease process," he added.

Source: ANI
RAS/L
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Health Benefits of Sea Buckthorn
Contraceptive Pills in Polycystic Ovary Syndrome (PCOS) Curtail Type 2 Diabetes Risk
Mushroom May Help Cut Down the Odds of Developing Depression
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Thalassemia Vasculitis Blood in Stools - Symptom Evaluation Bombay Blood Group 

Recommended Reading
Brain Tumor
Brain tumors are the abnormal growth of brain cells that may be benign or metastatic. Brain tumors ....
Protein Linked to Brain Disease Deciphered at Atomic Level
For the first time, Ohio State University researchers have taken an atomic-level look at the ......
Blood in Stools - Symptom Evaluation
Blood in stools results from bleeding that arises from any part of the digestive tract. Causes of bl...
Bombay Blood Group
Bombay blood group is a rare blood type in which the people have an H antigen deficiency. They can r...
Thalassemia
Thalassemia is an inherited blood disorder passed on through parental genes causing the body to prod...
Vasculitis
Vasculitis is an inflammation of the blood vessels of the body that can affect people of all ages; i...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use