Mice Grafted With Human Brain Cells Show Improved Learning Ability

In a recent research, scientists had grafted glia cells, a type of human brain cells, into the brains of baby mice and found that the implanted human cells developed inside the brains of the mice and made them smarter.

The mice with mutated brain cells were found to learn to escape traps at a faster rate when compared with their counterparts with normal brain.

Genetic Mutations Damage Brain Cells in Parkinson's Disease

In familial Parkinson's disease, scientists have discovered how the most common genetic mutations damage brain cells.

Astrocytes, a type of glial cells, were initially thought to be mere support cells without transporting signals. However, later it was reported that astrocytes in humans perform a more complex and are highly efficient in transmitting signals than those found in the brain of mice.

Maiken Nedergaard and Steve Goldman of the University of Rochester Medical Centre in New York in their experiment had incorporated astrocytes generating stem cells into the brains of baby mice. When the mice matured, the researchers tested the learning ability of the mice by conducting various experiments. The mice learnt to clear a maze, find objects and avoid mild electric shock at a much quicker pace.

Scientists opine that same technique could be used to explore human brain diseases by grafting glial progenitor cells taken from a person with the disorder.

Source: Medindia