About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Medications for Diabetes Mask Surgical Complication: Study

by Ramya Rachamanti on July 19, 2019 at 4:09 PM
Font : A-A+

Medications for Diabetes Mask Surgical Complication: Study

Novel anti-diabetic agents named gliflozins were found to mask a dangerous complication called ketoacidosis at the time of surgery. Blood test has to be done to check ketoacidosis in which there is lethal build-up of acid in the blood.

A study published in the British Journal of Anaesthesia found 42 cases of people with diabetes who presented for various surgeries, while taking gliflozin medications, experienced ketoacidosis while their blood sugar level was normal.

Advertisement


"Euglycaemic ketoacidosis is deceiving and likely to be missed easily as it presents with near or low-normal blood sugars," says Dr Venkatesan Thiru, Senior Clinical Lecturer, the University of Adelaide.

"Gliflozin medications are being increasingly used to protect people against heart and kidneys diseases. They work in the kidneys to excrete excess sugar in diabetic patients' urine.
Advertisement

"The condition may happen in the lead-up to surgery when patients cannot eat and drink normally.

"It is difficult to recognize euglycaemic ketoacidosis as blood sugar levels are usually normal."

Diabetic ketoacidosis is a serious complication when the body does not have enough insulin and can't use sugar to generate energy. Instead, the body uses fat to produce energy and this process leads to accumulation of acids called ketones in the body. Blood sugar levels are always high with this ketone build-up which is called diabetic ketoacidosis. If this problem is not treated, it can lead to coma and death. It is likely to happen with severe infection, loss of hydration, illness or during surgery.

"Euglycaemic ketoacidosis can happen in people with both type 1 and type 2 diabetes. Unless special tests are done to assess the acid load in the body, clinicians can miss this complication. The symptoms are similar to other events during and after surgery such as mild acid build up, vomiting and abdominal pain," says Dr Thiru.

"Failure to identify and treat this condition can result in unnecessary tests looking for other medical and surgical problems after surgery.

"In the 42 cases identified in the study, euglycaemic ketoacidosis occurred within a few hours after surgery and up to a few weeks after their operation. Changes in patients' diabetes medications, diet and illnesses were found to be responsible.

"Patients who undertake weight reduction surgery when they are on a special diet program are at an increased risk of experiencing this complication.

"Extra vigilance is the key in reducing this complication and patients should be educated about this. Care givers should ask for acid load to be tested by checking for blood ketone levels. The good news is that some of the latest blood glucose home monitoring kits can also test for acid build up.

"While the rate of this incident occurring in diabetic patients having surgery is unknown at this stage, our team is embarking on a study to assess the ongoing risk," says Dr Thiru.



Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
News Category
What's New on Medindia
January is the Thyroid Awareness Month in 2022
Menstrual Disorders
Coffee May Help You Fight Endometrial Cancer
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Diabetic Retinopathy Drug Toxicity Diabetes Diabetic Diet Diabetes - Essentials Diabetes - Self-Monitoring of Blood Glucose (SMBG) Insulin Delivery Devices Diabetes and Exercise Stress Relief Through Alternative Medicine Stress and the Gender Divide 

Recommended Reading
Diabetes - Oral Hypoglycemic Agents and Glycemic Control
Glycemic control in type 2 diabetes is achieved with oral diabetic medications. Combination drugs .....
Diabetes
A comprehensive article on diabetes - both Type 1 and Type 2 diabetes, including : causes, signs, sy...
Diabetes - Essentials
Diabetes is a metabolic disease caused by insulin deficiency that leads to high blood sugar levels a...
Diabetes - Self-Monitoring of Blood Glucose (SMBG)
Self-Monitoring Of Blood Glucose (SMBG) is one of the greatest advancements in the management of Di...
Diabetes and Exercise
Regular exercise especially in type II diabetes not only helps reduce the sugar but also reduces the...
Diabetic Diet
The diabetic diet most often recommended is high in dietary fiber (especially soluble fiber) and nut...
Diabetic Retinopathy
The term ‘diabetic retinopathy’ refers to changes in the retina which often occur in people with ......
Drug Toxicity
Drug toxicity is an adverse reaction of the body towards a drug that results as a side effect of a d...
Insulin Delivery Devices
Insulin delivery devices have evolved drastically since their invention in 1922. They are all aimed ...
Stress and the Gender Divide
Stress has become entwined in the current lifestyle of a young working couple and has resulted in th...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2022

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use
open close
ASK A DOCTOR ONLINE
I have read and I do accept terms of use - Telemedicine

Advantage Medindia: FREE subscription for 'Personalised Health & Wellness website with consultation' (Value Rs.300/-)