Researchers studied 22,405 pregnancies in the multiple micronutrient group and 22,162 pregnancies in the iron-folic acid group. They found that there were 14,374 and 14,142 live-born infants respectively. At 6 months, it was found that here was no significant reduction in infant mortality in multiple micronutrients group, with 764 deaths in the iron-folic acid group and 741 deaths in the multiple micronutrients group. Supplementation with multiple micronutrients resulted in a non-statistically significant reduction in stillbirths and significant reductions in preterm births and low birth weight.
The authors write, "Our study's null finding is in agreement with a small number of trials that have provided an antenatal multiple micronutrients vs. iron supplement, with or without folic acid, and found no effect on neonatal mortality. Reasons for a null effect on postnatal survival after improvement in some birth outcomes with antenatal multiple micronutrients supplement use remains unknown but may reflect a complex interplay between maternal and newborn sizes and differential responses to supplementation by causes of death."