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Many Patients With Rectal Cancer may Not Need Chemoradiotherapy: Study

by Colleen Fleiss on May 12, 2018 at 11:42 PM
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Many Patients With Rectal Cancer may Not Need Chemoradiotherapy: Study

New method discovered by researchers could reduce the number of patients who receive chemoradiotherapy by roughly half, with only a minimal risk of undertreatment.

It's unclear whether all patients with advanced rectal cancer need chemoradiotherapy, or whether some can forego the treatment and therefore be spared its side effects. A new BJS(British Journal of Surgery) study found that Investigators estimate that In the observational trial, 545 patients with cancer of the rectum were stratified into low-and high-risk groups. Chemoradiotherapy was administered to patients at high risk and was avoided in 42% of patients. The 3- and 5-year local recurrence rates of cancer were similarly low in patients who had surgery alone (a procedure called total mesorectal excision) versus patients who received chemoradiotherapy followed by surgery.

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"The results are an important step to an individualized therapy of rectal cancer," said co-author Prof. Theodor Junginger, of the University Medical Centre Mainz, in Germany. "The concept avoids adverse effects of chemoradiotherapy, shortens duration of treatment, and saves costs."

Source: Eurekalert
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