Major Depressive Episode and PTSD Appears to Increase Risk of Preterm Birth

Diagnoses of both a major depressive episode and posttraumatic stress disorder (PTSD) appear to be associated with a sizable increase in risk for preterm birth that seems to be independent of antidepressant and benzodiazepine medication use.

Diagnoses of both a major depressive episode and posttraumatic stress disorder (PTSD) appear to be associated with a sizable increase in risk for preterm birth that seems to be independent of antidepressant and benzodiazepine medication use.

Preterm birth is responsible for many infant deaths. Clinicians and patients are concerned about the risks associated with psychiatric illness during pregnancy and the medications used for treatment.

Factors Determining Risk for Preterm Birth
Shorter birth spacing between previous delivery and coming conception could be a risk factor for shorter pregnancy length, and a risk for preterm birth, demonstrated researchers.

The study included a group of 2,654 pregnant women recruited before 17 weeks gestation. The authors looked for PTSD, major depressive episode, and the use of antidepressant and benzodiazepine medications. They measured preterm births, defined as birth before 37 weeks gestation.

Of the women, 129 (4.9 percent) had symptoms consistent with PTSD. Pregnant women with both PTSD and a major depressive episode had a four-fold increased risk of preterm birth. Each one-point increase on a scale measuring PTSD symptoms increased the risk for preterm birth by 1 percent to 2 percent. Women prescribed serotonin reuptake inhibitor and benzodiazepine medications had higher odds for preterm birth.

"The risk appears independent of antidepressant or benzodiazepine use and is not simply a function of mood or anxiety symptoms. Further exploration of the biological and genetic factors will help risk-stratify patients and illuminate the pathways leading to this risk."

Risk of Preterm Birth Significantly Higher Among Expecting Mothers Who Followed Poor Diet Before Pregnancy
The risk of preterm birth is 50 percent higher among expecting mothers who eat a poor diet before getting pregnant, a new study reveals.

Source-Eurekalert

Prediction of Impending Preterm Birth may be Helped by Novel Blood Test
Predictions whether 70% of female study participants with threatened preterm labor (TPIL) would or would not give birth prematurely has been done with a blood based diagnostic test.

Preterm Births and Fertility Treatment
While fertility treatments may be a leading cause of increase in multiple gestation, the results are not inevitable, a study recently found.