Improvements to health remain even if weight is regained after long-term healthy dietary interventions, say researchers. Long-term healthy dietary interventions frequently induce a rapid weight decline, mainly in the first four to six months, followed by weight stabilization or regain, despite continued dieting. The partial regain may discourage people from adhering to healthier habits, but research now shows that improvements to health remain, regardless of partial weight regain. The study identified two distinct biomarker patterns that correspond to weight change, one of which continues to improve with time. The study was conducted among 322 participants during the two-year Dietary Intervention Randomized Controlled Trial (DIRECT) performed by Ben-Gurion University of the Negev at the Nuclear Research Center Negev, Israel (New England Journal of Medicine). The population was randomised to three different, but healthy interventions: low-fat, Mediterranean or low-carbohydrate diets, and unprecedented adherence rates were maintained throughout the entire two-year period. "This study tells us that we may all have tunnel vision on weight when it comes to healthy dieting. Although maintaining ideal body weight is linked to better health, when it comes to adopting healthier dietary habits in mild to moderately obese people, there are benefits beyond weight loss, such as decreasing inflammatory tone and elevating the 'good cholesterol' HDL," said BGU Faculty of Health Sciences Prof. Assaf Rudich. Rudich explains that switching to healthier dieting extends benefits beyond the single outcome of weight loss. In fact, important improvements that likely signify decreased risk for cardiovascular disease occur even despite weight regain, as long as dieting continues. The researchers identified two distinct patterns:Pattern-A" includes biomarkers [insulin, triglycerides, leptin, chemerin, monocyte-chemotactic-protein-1(MCP-1), and retinol-binding-protein-4(RBP4)] whose dynamics tightly corresponded to changes in body weight. "Pattern B" that includes high-molecular-weight (HMW) [adiponectin, HDL-cholesterol, high-sensitive C-reactive protein (hsCRP), fetuin-A, progranulin, and vaspin], which displayed a continued, cumulative improvement throughout the intervention, despite the partial weight regain observed during months 7-24 of continued dieting, a totally different pattern of biomarkers. These patterns were similar, although of different magnitude, across the low-carb, Mediterranean and low-fat diets. The study was recently released online in Diabetes Care.Source: ANI << PCs and Phones Geared by Mind Step Next to Reality Aggression Levels Raised by Winning Fights >> Recommended Reading Low Calorie Diet Low calorie meals or diet include foods that are high on nutritional content and yet have fewer calories. Updated information about low calorie diet or low calorie foods and its health benefits. READ MORE Macrobiotic Diet Macrobiotics is an Oriental theory that lays down guidelines for promoting well-being and longevity through systematic diet consisting mainly of whole grains and beans. READ MORE South Beach Diet South Beach Diet plan originally developed to prevent heart disease, soon gained popularity as weight loss diet plan. This diet plan was developed by Dr.Arthur Agaston and Marie Almon. READ MORE Battle of the Bulge The ‘battle of bulge’ is the toughest of all battles. Once you put on weight it is so difficult to get rid of it. Here are the best tips to fight off that extra flab. READ MORE Bulimia Nervosa The term ''Bulimia'' refers to episodes of uncontrolled excessive eating, known as "binges," followed by self-induced vomiting or purgation. READ MORE Diet and Nutrition for Healthy Weight Loss Correct diet and a planned exercise regime is the mantra of healthy and sustainable weight loss. READ MORE Diet Pills Diet pills are flooding the market by millions. The positive side of diet pills to most people is that they achieve their objective of losing weight. Medical reviews are against the use of diet pills. READ MORE Hunger Fullness and Weight Control An erratic way of eating or any metabolic disturbance in the hunger fullness signals is one of the major causes of obesity. READ MORE The Cabbage Diet The plausible reason that can be sited is the inherent low calorie property of cabbage. READ MORE Weight Loss Program For Men Maintaining a food diary and keeping a track of what you eat is the best way to keep your weight under check. READ MORE Weight Loss with Hypnosis – Does It Work? Hypnosis indirectly helps with weight loss by altering the consciousness through suggestions and imagery to a more positive state. READ MORE Most Popular on Medindia Drug Side Effects Calculator Accident and Trauma Care Loram (2 mg) (Lorazepam) More News on: Diet PillsThe Cabbage DietBulimia NervosaThe Macrobiotic DietHeight and Weight-KidsWeight Loss Program For MenBattle of the BulgeHunger Fullness and Weight ControlDiet and Nutrition for Healthy Weight LossWeight Loss with Hypnosis – Does It Work?