About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Longer Life Found in Mice Linked to Taking Human Dietary Supplement

by Himabindu Venkatakrishnan on April 9, 2014 at 1:07 PM
Font : A-A+

 Longer Life Found in Mice Linked to Taking Human Dietary Supplement

The lifespan of lab mice was prolonged by nearly a tenth with an over-the-counter supplement designed to ease osteoarthritis, said scientists on Tuesday.

This would translate into an average eight-year longevity gain if the result could be repeated in humans, Swiss researchers reported in the journal Nature Communications.

Advertisement

A team led by Michael Ristow at the Swiss Federal Institute of Technology (ETH) in Zurich used a common dietary supplement called glucosamine on laboratory mice after testing it on worms.

Glucosamine is a naturally occurring compound found in the lubricating fluid which surrounds joints.

It is widely sold over the counter as a supplement to combat osteoarthritis, the commonest form of arthritis, although studies into its efficacy have thrown up mixed results.
Advertisement

Ristow's team first tested a tiny dose on a well-researched lab animal, a nematode worm called Caenorhabditis elegans, and found it extended its lifespan by some five percent.

They then experimented with 146 mice just under two years old -- the rough equivalent of 65 years in human terms.

Mice given glucosamine lived on average 10 percent longer than counterparts who did not get the supplement, which in human terms is about eight years.

Additional work in lab dishes suggested glucosamine had a big effect on the metabolic system, the scientists said.

It prevents the breakdown of large sugar molecules into smaller ones, thus replicating a "low-carb" diet that restricts intake of carbohydrates.

Further work is needed to explain why this appears to affect the mice's longevity -- and to see whether the benefit extends to humans.

"If an even modest effect on ageing were proven, it would be a major advance," Tim Spector, a genetic epidemiologist at King's College London, said in an independent comment.

"However, humans are not the same as worms or rodents, and studies will need careful replication before we get over-excited."

Source: AFP
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Health Benefits of Sea Buckthorn
Contraceptive Pills in Polycystic Ovary Syndrome (PCOS) Curtail Type 2 Diabetes Risk
Mushroom May Help Cut Down the Odds of Developing Depression
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Spirulina Undetected Nutrient Deficiencies: the Cause of Ill Health Diet and Nutrition Tips for Athletes Promote Your Health with Nutrition Supplements 

Recommended Reading
Dietary Supplements - Dieticians Recommend and Use It Too: Survey
Health professionals recommend dietary supplements to patients but do they take it themselves? If .....
Probiotics - Support System for the Gut
Probiotics are live microorganisms that resemble the "good bacteria" in our gut. Science is yet to ....
Are Dietary Supplements Beneficial in Smokers?
Dietary supplements bring about certain metabolic changes in smokers, according to a recent study....
Diet and Nutrition Tips for Athletes
Athletes can be physically fit by consuming a well balanced nutritious diet, which keeps them mental...
Promote Your Health with Nutrition Supplements
As a part of preventive care one should take a good quality nutritional supplement containing antiox...
Spirulina
Spirulina is a blue-green algae that is grown globally as a health supplement. Of late there is an e...
Undetected Nutrient Deficiencies: The Cause of Ill Health
Micronutrient and antioxidant deficiencies are most common and go unnoticed. They are the root cause...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use