About Careers MedBlog Contact us

Long-term Brain Disorders Linked To Teen Meth Abuse

by Ann Samuel on August 15, 2007 at 1:56 PM
Font : A-A+

Long-term Brain Disorders Linked To Teen Meth Abuse

Young adults who use methamphetamine could be more prone to age-related brain diseases long after they stop using the drug, according to new animal research published Tuesday.

Scientists were working on the previous hypothesis that early meth abuse can cause the same symptoms as those experienced by Parkinson's disease patients who are missing a key protein, said the findings in the journal Neuroscience.


For the study, researchers gave two groups of young mice either methamphetamine or saline injections four times over an eight-hour period.

One group of mice was normal, the other had a partial depletion of glial derived neurotrophic factor (GDNF), a protein that protects and repairs dopamine, an important neurotransmitter, in areas of the brain related to motor control.

Loss of nerve cells that produce dopamine is a major contributor to Parkinson's disease.

The mice were 2.5 months old, or adolescents, at the start of the study. At 12 months old, the GDNF-depleted mice moved significantly less than the normal mice that got the same meth injections, according to the study.

Additionally, the immediate effects of the meth binge were exacerbated in the mice with the GDNF depletion.

"These studies speak directly to the possibility of long-term public health consequences resulting from the current epidemic of methamphetamine abuse among young adults," said Jacqueline McGinty, researcher at the Medical University of South Carolina, who led the study.

The study was funded by the US Army and National Institutes of Health.

Meth, also called speed, crystal or ice, is a highly addictive stimulant that increases wakefulness and suppresses appetite. It can be taken as a pill, smoked, snorted or injected. Long-term use can lead to hallucinations and stroke.

Nearly 12 million Americans have tried meth, according to a 2004 federal survey on drug use. Among teens, 6.2 percent of 17- and 18-year-olds in the United States said they have tried meth at least once.

Source: AFP


Recommended Reading

Latest Research News

Eight Threats to Black Adult's Longevity
Decoding the eight factors affecting Black adults' life expectancy.
Beyond the Campus: Contrasting Realities Revealed!
Sobering truth about foot travel in the United States emerges from international statistics, highlighting the prevalence of walking on the Blacksburg campus.
Astounding Link Between Darwin's Theory and Synaptic Plasticity — Discovered!
Unveiling a hidden mechanism, proteins within brain cells exhibit newfound abilities at synapses, reinforcing Darwin's theory of adaptation and diversity in the natural world.
Unlocking the Fountain of Youth: Exploring the Synergistic Power!
Combining micro-needling and cupping, two emerging and alternative techniques, in an experimental study reveals a potential synergy for skin rejuvenation.
Imminent Threat of the Next Pandemic - Disease X
Despite a decline in COVID-19 cases, the World Health Organisation (WHO) raises global concerns by warning of an "inevitable" next pandemic known as "Disease X".
View All
This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close

Long-term Brain Disorders Linked To Teen Meth Abuse Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests