Even though recipients who received liver grafts from older donors (70 and older) had improved outcomes with reduced mortality, graft loss and postoperative complications after transplantation, there is a decline in the use of liver grafts from older donors, finds a study. The results of the research are published in the journal JAMA Surgery. More than 10 percent of patients waiting for a liver transplant die each year. This observational study looked at trends in the transplantation of livers from older donors (70 and older) and outcomes in recipients of these older livers from 2003 to 2016. There was a decrease in the use of liver grafts from older donors despite improvements in liver graft loss and death among recipients of these older liver grafts. The study included 4,127 liver grafts from older donors and 3,350 liver-only recipients of these older liver grafts, and 78,990 liver grafts from younger donors (18 to 69) and 64,907 liver-only recipients of these younger liver grafts. A limitation of the study was the inability to determine whether the improvement in outcomes was associated with improved post-transplant care or improved older donor candidate selection. The findings suggest it may be reasonable to expand the donor pool with broader use of liver grafts from older donors. ‘Liver transplantation is the usually reserved treatment option for people with end-stage chronic liver disease or liver failure.’ Source: Eurekalert << Novel AI Toolkit Analyzes Infectious Pathogens in Few Minute... Poor Sleep May Clog Your Arteries and Increase the Risk of H... >> Recommended Reading Common Types of Liver diseases leading to Liver Transplantation Liver disease that ends in liver failure (end stage liver disease), disrupting several important metabolic functions needs liver transplant for patient survival. READ MORE Liver Transplantation Liver transplantation is a surgical option for the treatment of liver failure where the diseased liver is replaced with a healthy one. READ MORE Current Treatments for Liver Cancer Current Treatments for Liver Cancer (also known as hepatoma or hepatocellular carcinoma) can result in complete cure of the disease if it is detected early. READ MORE Fatty Liver Disease: A Growing Health Problem in India Non alcoholic fatty liver disease (NAFLD) is the leading cause of liver dysfunction worldwide and is a rapidly growing health problem in India. READ MORE Hepatitis A Hepatitis A is the most benign of the hepatitis viruses and usually has no long term side effects. Hepatitis A vaccine is available that is 95% effective in preventing the disease. READ MORE Living Donor Liver Transplant: What Are the Risks? The risk of dying as a result of a living donor liver segment removal is between 0.2-2.0%. The risk of morbidity is anywhere between 1.3% (in highly experienced centers) to 60%. READ MORE Milk Thistle Milk Thistle is a resourceful natural plant which has many medicinal benefits. In herbal medication milk thistle is used in cases of liver diseases. READ MORE Wilson's Disease This is a rare inherited systemic disorder of copper metabolism, affecting the liver mainly before other organs. READ MORE Most Popular on Medindia How to Reduce School Bag Weight - Simple Tips Drug Side Effects Calculator Sanatogen More News on: Hepatitis ALiverWilson's DiseaseMilk ThistleCurrent Treatments for Liver CancerFatty Liver Disease: A Growing Health Problem in IndiaLiving Donor Liver Transplant: What Are the Risks?