Low sodium levels or hyponatremia, prior to transplantation does not seem to increase the risk of death following liver transplant, report researchers. Full findings are published in Liver Transplantation, a journal of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. Medical evidence shows that low sodium concentration is common in patients with end stage liver disease (ESLD), with roughly half of those with cirrhosis having sodium levels below the normal range of 135-145 mmol/L. Moreover, previous research suggests that hyponatremia is linked to complications including bacterial infections, kidney failure and encephalopathy, and increases mortality in patients with ESLD. Following liver transplantation sodium levels will return to normal. "There is much debate within the transplant community about whether to incorporate measures of serum sodium in the organ allocation system in the U.S.," explains lead author Dr. W. Ray Kim from Stanford University in Calif., and formerly with the Mayo Clinic where the research took place. "Understanding the impact of sodium concentrations in patients prior to and following liver transplantation is an important contribution to this debate." Using data from the Organ Procurement and Transplantation Network (OPTN) researchers identified 19,537 patients 18 years of age or older who received a liver transplant in the U.S. between 2003 and 2010. Subjects were split into three groups: those with hyponatremia (sodium levels less than 130 mEq/L); normal sodium levels (serum sodium between131-145mEq/L); and hypernatremia (high sodium levels great than 145mEq/L). "While our findings confirm that low sodium levels prior to transplant were a strong risk factor for waitlist mortality it was not associated with higher death risk following liver transplantation," concludes Dr. Kim. "Our data suggests that using serum sodium levels to determine organ allocation priority will not impact survival following a liver transplant." Source: Eurekalert << Study Of Caloric Restriction In Monkey Shows Big Benefit, C... Legal Pitfalls of Korean Unification Seen in Inheritance Ca... >> Recommended Reading Liver Transplant may be the Answer for Lathosterolosis Liver transplant may help to cure lathosterolosis, reveals a recent case report. READ MORE Vitamin D may Help Prevent Progress of Liver Fibrosis The findings of a recent animal study have revealed that synthetic vitamin D is effective in preventing the progress of liver fibrosis. READ MORE Liver can be Damaged by Cinnamon Recent researches show that cinnamon is harmful for liver. In olden days cinnamon was not just a spice it was even used as currency and is known to have unmatched aphrodisiacal prowess. READ MORE Quiz on Liver How many of us know that the liver is a vital organ the size of an American Football? To understand more about the liver and its functions spend a few minutes taking part in this ... READ MORE Current Treatments for Liver Cancer Current Treatments for Liver Cancer (also known as hepatoma or hepatocellular carcinoma) can result in complete cure of the disease if it is detected early. READ MORE Fatty Liver Disease: A Growing Health Problem in India Non alcoholic fatty liver disease (NAFLD) is the leading cause of liver dysfunction worldwide and is a rapidly growing health problem in India. READ MORE Hepatitis A Hepatitis A is the most benign of the hepatitis viruses and usually has no long term side effects. Hepatitis A vaccine is available that is 95% effective in preventing the disease. READ MORE Hyponatremia Hyponatremia is an electrolyte imbalance causing low blood sodium levels. It is a dangerous condition that causes fluid retention in the brain leading to coma or even death. The causes, symptoms and treatment of hyponatremia are described below. READ MORE Living Donor Liver Transplant: What Are the Risks? The risk of dying as a result of a living donor liver segment removal is between 0.2-2.0%. The risk of morbidity is anywhere between 1.3% (in highly experienced centers) to 60%. READ MORE Milk Thistle Milk Thistle is a resourceful natural plant which has many medicinal benefits. In herbal medication milk thistle is used in cases of liver diseases. READ MORE Sclerosing Cholangitis Sclerosing cholangitis is a liver disease characterized by inflammation and scarring of bile ducts within and outside the liver resulting in their constriction. READ MORE Wilson's Disease This is a rare inherited systemic disorder of copper metabolism, affecting the liver mainly before other organs. READ MORE Most Popular on Medindia Color Blindness Calculator Blood Donation - Recipients Post-Nasal Drip More News on: Hepatitis ALiverWilson's DiseaseSclerosing CholangitisDrugs Causing Low Sodium Levels / HyponatremiaHyponatremiaMilk ThistleCurrent Treatments for Liver CancerFatty Liver Disease: A Growing Health Problem in IndiaLiving Donor Liver Transplant: What Are the Risks?