In a mouse study, association between zinc deficiency, blood pressure and kidney sodium transporter was identified. The study is published ahead of print in the American Journal of Physiology--Renal Physiology.
Zinc deficiency is common in people with chronic illnesses such as type 2 diabetes and chronic kidney disease. People with low zinc levels are also at a higher risk for hypertension.
The way in which the kidneys either excrete sodium into the urine or reabsorb it into the body--specifically through a pathway called the sodium chloride cotransporter (NCC)--also plays a role in blood pressure control.
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‘Understanding the specific mechanisms by which zinc deficiency contributes to blood pressure dysregulation may have an important effect on the treatment of hypertension in chronic disease settings. ’
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Less sodium in the urine typically corresponds with higher blood pressure. Recent research has suggested that zinc may help regulate proteins that in turn regulate the NCC, but a direct link between zinc-deficiency-induced hypertension has not been examined.
Researchers compared male mice with zinc deficiency to healthy controls with normal zinc levels. The zinc-deficient mice developed high blood pressure and a corresponding decrease in urinary sodium excretion. The control group did not experience the same changes. A small group of the zinc-deficient mice were fed a zinc-rich diet partway through the study.
![Foods High in Zinc]( "Foods High in Zinc")
Zinc is needed in small amounts every day for good health. Here are some zinc-rich foods for both men and women to lead a healthy life.
Once the animals' zinc reached adequate levels, blood pressure began to drop and urinary sodium levels increased. "These significant findings demonstrate that enhanced renal [sodium] reabsorption plays a critical role in [zinc-deficiency]-induced hypertension," the research team wrote.
Source: Eurekalert
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Zinc is needed in small amounts every day for good health. Here are some zinc-rich foods for both men and women to lead a healthy life.
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Once the animals' zinc reached adequate levels, blood pressure began to drop and urinary sodium levels increased. "These significant findings demonstrate that enhanced renal [sodium] reabsorption plays a critical role in [zinc-deficiency]-induced hypertension," the research team wrote.
Source: Eurekalert
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In India alone, about 80 percent of pregnant women, 52 percent of non-pregnant women, and 74 percent of children in the 6-35 months age group suffer from iron deficiency.
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