About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Link Between Hallucinations, Dopamine Discovered

by Colleen Fleiss on February 19, 2018 at 3:01 AM
Font : A-A+

Link Between Hallucinations, Dopamine Discovered

New study finds people with schizophrenia, who experience auditory hallucinations, tend to hear what they expect an exaggerated version of a perceptual distortion.

"Our brain uses prior experiences to generate sensory expectations that help fill in the gaps when sounds or images are distorted or unclear," said Guillermo Horga, Assistant Professor at Columbia University Medical Centre.

Advertisement


"In individuals with schizophrenia, this process appears to be altered, leading to extreme perceptual distortions, such as hearing voices that are not there," Horga added.

For the study, published in the journal Current Biology, researchers designed an experiment that induces an auditory illusion in both healthy participants and participants with schizophrenia.
Advertisement

They examined how building up or breaking down sensory expectations can modify the strength of this illusion. They also measured dopamine release before and after administering a drug that stimulates the release of dopamine.

Patients with hallucinations tended to perceive sounds in a way that was more similar to what they had been cued to expect, even when sensory expectations were less reliable and illusions weakened in healthy participants, the researcher said.

This tendency to inflexibly hear what was expected was worsened after giving a dopamine-releasing drug, and more pronounced in participants with elevated dopamine release, and more apparent in participants with a smaller dorsal anterior cingulate -- a brain region previously shown to track reliability of environmental cues).

"All people have some perceptual distortions, but these results suggest that excess dopamine can exacerbate our distorted perceptions," said Horga.

Source: IANS
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
News Category
What's New on Medindia
International Day of Persons with Disabilities 2021 - Fighting for Rights in the Post-COVID Era
Effect of Blood Group Type on COVID-19 Risk and Severity
Woman with Rare Spinal Cord Defect from Birth Sues Doctor
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.


Recommended Reading
Hallucinations
Hallucinations or false perceptions, are often associated with mental disorders and neurological ......
Quiz on Schizophrenia
Schizophrenia is a mental disorder that affects young adults; nearly 7% of the adult population ......
Here's Why People With Parkinson's Have Hallucinations
Disconnection in the areas of the brain, which are involved in attention and visual processing ......
Hallucinations Linked to Structural Differences in the Brain
People who hallucinate have structural differences in the brain compared to healthy individuals and ...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use