About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Leptin: Key Predictor of Maternal Weight Gain During Pregnancy

by Colleen Fleiss on March 20, 2018 at 2:03 AM
Font : A-A+

Leptin: Key Predictor of Maternal Weight Gain During Pregnancy

Weight gain during pregnancy can be predicted by certain measures. Leptin levels in mid-pregnancy may be a key predictor of weight gain during pregnancy, suggests research. The results are presented in a poster at ENDO 2018, the 100th annual meeting of the Endocrine Society in Chicago, Ill.

"Gaining too much or too little weight during pregnancy poses potential health risks. Leptin and adiponectin, hormones released primarily from fat cells, are known to play roles in appetite regulation, insulin resistance, lipid metabolism, blood pressure and the development of metabolic syndrome," said lead study author Adam Jara, D.O., Ph.D., a clinical instructor at Ohio State University in Columbus, Ohio.

Advertisement


Jara and his co-authors at Ohio State investigated the effects of race and pre-pregnancy BMI on serum adiponectin, leptin, the leptin-to-adiponectin ratio (LAR) throughout pregnancy and postpartum, and their effects on weight gain during pregnancy.

The research team recruited 80 pregnant women--38 African-American and 42 Caucasian women--from the Ohio State University Medical Center Prenatal Clinic. The authors measured adiponectin and leptin levels 3 times during pregnancy--early, middle and late--and again after delivery.
Advertisement

Both race and pre-pregnancy BMI appeared to affect adiponectin and leptin levels during pregnancy and after birth.

After controlling for race and pre-pregnancy BMI, serum levels of adiponectin, leptin and the LAR during pregnancy predicted total maternal weight gain. Leptin levels in mid-pregnancy were the most predictive of weight gain during pregnancy.

Among African-American women with obesity, the LAR increased significantly from early to mid-pregnancy, stayed high in late pregnancy and decreased after birth. By contrast, among Caucasian women with obesity, the LAR did not change significantly over time.

Overall, adiponectin levels decreased from early to late pregnancy, with an increasing trend after birth. Higher pre-pregnancy BMI was associated with lower levels of adiponectin. African-American women had lower serum adiponectin at each time point they were tested, compared to Caucasian women with equivalent pre-pregnancy BMIs.

Overall, serum leptin increased throughout pregnancy and declined after birth. Lower leptin levels were associated with lower pre-pregnancy BMIs.

The National Institute of Nursing Research (NINR), the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), the National Center for Advancing Translational Sciences (NCATS), and an Ohio University Transition to Research Independence Award supported the study.

Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
News Category
What's New on Medindia
International Day of Persons with Disabilities 2021 - Fighting for Rights in the Post-COVID Era
Effect of Blood Group Type on COVID-19 Risk and Severity
Woman with Rare Spinal Cord Defect from Birth Sues Doctor
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Trimester of pregnancy Pregnancy and Exercise Home Pregnancy Test Pregnancy Zone Diet Psychological Changes In Pregnancy Height and Weight-Kids Drugs in Pregnancy and Lactation Breech Presentation and Delivery Air travel: To fly or not to fly 

Recommended Reading
Healthy Weight Gain during Pregnancy
Recommended weight gain during pregnancy is determined as per pre-pregnancy weight and BMI. Healthy ...
Pregnancy Weight Gain Calculator
Calculate your weight gain during pregnancy and find out the ideal weight gain limit for your month ...
Top 7 Fruits to Eat During Pregnancy
Make it a habit to incorporate at least 2 serving of fruits every day during pregnancy to reap the ....
Learn About Pregnancy - Animation
Pregnancy Labor is caused by series of progressive expulsive contractions by the uterus and results ...
Air travel: To fly or not to fly
Air travel is for everyone, even those with medical conditions....
Breech Presentation and Delivery
Breech birth or presentation is delivery of the fetus in a bottom or foot-first position. Causes of ...
Drugs in Pregnancy and Lactation
During pregnancy & lactation a nutritious diet, suitable exercise, adequate rest and a tranquil mind...
Home Pregnancy Test
A home pregnancy test is a test done to find out if one is pregnant or not in the relative comforts ...
Pregnancy
Detailed look at Early pregnancy Symptoms and easy health solutions during 1st, 2nd and 3rd trimeste...
Psychological Changes In Pregnancy
Pregnancy is an experience of growth, change, enrichment and challenge. During the 40 weeks of pregn...
Trimester of pregnancy
Encyclopedia section of medindia explains in brief about confirmation of pregnancy in first ......
Zone Diet
The Zone Diet is a weight loss program with a ‘40:30:30’ plan for carbohydrates, fats and proteins ....

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use