Late-breaking sessions of the AACC Annual Scientific Meeting & Clinical Lab Expo will deliver insights into the latest advances are transforming healthcare.
First-in-Human Use of CRISPR for Cancer Treatment Approved in the US
US regulatory has approved the first human clinical trial using the breakthrough gene editing technique, CRISPR/Cas9.
US regulatory has approved the first human clinical trial using the breakthrough gene editing technique, CRISPR/Cas9.
‘Healthcare has leapt forward this year with a wide range of breakthroughs, from new technologies that will make it easier for people to get vital test results, to advances in gene editing that could give hope to patients with incurable genetic diseases.’
CRISPR. Short for "clustered regularly interspaced short palindromic repeats," CRISPR has made genome editing easy by enabling researchers to quickly and precisely cut and paste segments of DNA. This technique shows incredible promise, and could potentially be used to treat conditions ranging from inherited vision loss to HIV. In the scientific session, "Correcting Nature's Mistakes and Beyond: The Promise of Gene Therapy," experts will examine how CRISPR could be used to enhance immunotherapy by genetically editing the body's T cells and instructing them to detect and destroy cancer cells. In addition, attendees will hear about the use of gene editing and adeno-associated virus-based gene therapy to treat genetic disease.
Disruptive technology. Central laboratories operate under space, time, and transport limitations that can hinder patient access to crucial tests, but innovations are on the horizon that could lift these constraints and make the patient testing experience better than ever. Soon, drones could make laboratory testing accessible in remote areas by collecting samples from patients directly and transporting them to labs. Major tests could potentially be performed right at the patient's bedside because immense mass spectrometers have been shrunk down to fit in the palm of one's hand and coupled with microfluidics; and now that nucleic acid testing can be done in less than one minute. And alternative ways to obtain blood samples could eliminate the need for patients to undergo painful venous blood draws.
Antibiotic Resistance may be Promoted by CRISPR System
Antibiotic resistance in Francisella novicida, a close relative of a bacterium that causes tularemia, is promoted by a system of genes that bacteria use to fend off viruses
Antibiotic resistance in Francisella novicida, a close relative of a bacterium that causes tularemia, is promoted by a system of genes that bacteria use to fend off viruses
Hepatitis C. Despite a revolution in treating hepatitis C, many in medicine question whether new, curative therapies mean the end of this epidemic. Three special sessions at the meeting will explore treatment and prevention; a debate on the future of hepatitis C; and the latest science on laboratory testing for this disease.
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Accuracy of CRISPR-Based Systems Increased by New Genome-Editing Platform
Investigators have developed a next-generation genome editing system that substantially decreases the risk of producing unwanted, off-target gene mutations.
Investigators have developed a next-generation genome editing system that substantially decreases the risk of producing unwanted, off-target gene mutations.
Source-Newswise
A Guide to CRISPR Gene Activation by Wyss Institute
The CRISPR-Cas9 system has come to be known as the quintessential tool that allows researchers to edit the DNA sequences of many organisms and cell types.
The CRISPR-Cas9 system has come to be known as the quintessential tool that allows researchers to edit the DNA sequences of many organisms and cell types.
