Blood fat metabolism could go wrong in patients with kidney disease. That could mean increased risk of heart disease for them, an Australian study shows.
High blood fat levels are linked to increased risk of heart disease which can be made worse by resistance of tissues to insulin action (insulin resistance) and central obesity, it is pointed out.
World Kidney Day – 2009
“Keep the pressure down is the slogan for the World Kidney Day 2009. It points to the importance of high blood pressure as a primary cause of kidney disease.
“Keep the pressure down is the slogan for the World Kidney Day 2009. It points to the importance of high blood pressure as a primary cause of kidney disease.
By monitoring the production and breakdown of apolipoprotein B in people with kidney disease who were not centrally obese and had a similar degree of insulin resistance, Dr Chan found that subjects with early kidney disease had a principal defect in their ability to break down apolipoprotein B without increasing its production, leading to increased blood fat concentration.
"Thus, strategies to stop the breakdown of these apolipoproteins may lead to improved and more effective management of abnormal blood fat metabolism and potentially reduce the risk of heart disease in this high risk population," Dr Chan said.
The findings have been published in the prestigious Journal of Lipid Research.
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Know The Urinary System
Interactive section of Medindia gives general information about Male Urinary System.
Interactive section of Medindia gives general information about Male Urinary System.
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