'Key Player In Flu Outbreaks' Is Human Behavior: Study

Changes in human behavior may have the greatest influence on waves of influenza outbreak suggests a new study. Why flu arrives in multiple waves like the three waves of the deadliest influenza pandemic in history, known as the Spanish flu, which hit England and Wales in 1918, is the focus of a study by McMaster University researchers who discovered three contributing factors - the closing and opening of schools, temperature changes and - most importantly - changes in human behavior.

"We found all three factors were important in 1918 but that behavioural responses had the largest effect," David Earn, an investigator with the Michael G. DeGroote Institute for Infectious Disease Research, and a professor in McMaster's Department of Mathematics and Statistics, said.

The researchers did not measure behavioural change directly. Instead, their model showed that the three waves could only be explained if people reduced infectious contact rates when recent influenza mortality was high.

Possible mechanisms include avoiding large gatherings, keeping distance from other people, and hand-washing.

The study's findings are significant as global health officials keep watch on an emerging virus, Middle East Respiratory Syndrome (MERS), which is said to be more deadly than Severe Acute Respiratory Syndrome (SARS) and has already spread from Saudi Arabia to France, Germany, Italy and Britain.

Dr. Margaret Chan, director-general of the World Health Organization, has called MERS a "threat to the entire world".

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To investigate factors underlying the three-wave shape of the 1918 influenza epidemic, McMaster researchers developed what they describe as a simple epidemic model.

It incorporates three factors in addition to natural disease spread: school terms, temperature changes during an outbreak and changes in human behavior.

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The study is published online in the Proceedings of the Royal Society.

Source-ANI