Ketone nutritional supplements do not improve athletic performance during short-duration and high-intensity exercises, reveals a new study.
In the quest to improve physical performance, many athletes are turning to untested nutritional supplements. Recently, a research conducted from UBC's Okanagan campus on one popular class of supplements called ketone salts.
"Ketone salts are relatively new to the market and there's not much research on their impact on performance," says the study's co-author Jonathan Little, assistant professor in UBC Okanagan's School of Health and Exercise Sciences.
"It turns out that ketone salt supplements actually impair high-intensity exercise performance."
Ketone salts work by artificially elevating blood ketone levels, similar to what happens naturally during periods of starvation, and forces the body to rely on burning fat as a fuel, explains Little.
Burning fat is a more effective long-term fuel but is more complex to process and isn't as readily accessible for quick bursts of muscle activity as is a fuel like glucose.
"Elevated blood ketones seem to inhibit the body's use of glycogen, the stored form of glucose, and favours burning fat instead," adds Little. "That means that the body's quick-burning fuel cannot be accessed during high-intensity bursts of activity and athletic performance is dropping off as a result."
In his study, Little recruited ten healthy adult males with similar athletic abilities and body mass indices. After a period of fasting, they were asked to consume either beta-hydroxybutyrate ketone salts or a flavour-matched placebo, in a randomized order, and then engage in a cycling time trial. Power output on the day participants consumed ketone salts was seven per cent lower than on the day when they consumed the placebo.
"Often these supplements are marketed as a means of improving athletic performance but in this case, the research tells a very different story," says Little.
"On top of that, the long-term impacts of artificially increasing blood ketone levels essentially tricking the body into thinking it is in a state of starvation is completely unknown."
"I hope this helps athletes navigate the science of supplements rather than relying on label marketing alone."