About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Just One Dose of HPV Vaccine may be Enough to Prevent Cervical Cancer

by Kathy Jones on November 4, 2013 at 9:23 PM
Font : A-A+

 Just One Dose of HPV Vaccine may be Enough to Prevent Cervical Cancer

Even a single dose of vaccine that protects against the sexually transmitted disease HPV could be enough in significantly reducing risk of cervical cancer, a new study reveals.

The findings may lead to simpler delivery and lower costs, possibly increasing the number of young people who get vaccinated, said the report in the journal Cancer Prevention Research, released Monday.

Advertisement

The HPV vaccine is recommended for girls and boys before they become sexually active, but US research from 2012 showed that only one third of US female teens and fewer than seven percent of US boys got the recommended three doses.

"Our findings suggest promise for simplified vaccine administration schedules that might be cheaper, simpler, and more likely to be implemented around the world," said Mahboobeh Safaeian, an investigator in the Division of Cancer Epidemiology and Genetics at the National Cancer Institute in Maryland.
Advertisement

The study focused on a population of nearly 7,500 women aged 18-25 in Costa Rica. Although all were supposed to get the recommended three doses of the HPV vaccine at different times, about 20 percent of participants did not.

So researchers analyzed blood samples from a group of 78 who got one dose, compared to groups of 120 to 192 that received two or three doses as planned.

They found that all the women in all three groups had antibodies against virulent strains of HPV, known as 16 and 18.

These antibodies persisted in their blood for up to four years, which is about as long as researchers have expected the vaccine to be effective.

The levels of antibodies also appeared stable over time, even though they were slightly lower in the single dose group, suggesting "these are lasting responses," said the study.

The vaccine used in the study was Cervarix, made by the British pharmaceutical giant GlaxoSmithKline.

"GSK is continuing to review findings from this trial and is committed to ensuring regulatory authorities and public health officials have access to this information," a company spokesman told AFP.

Study authors said antibody responses after a single dose have not been evaluated for Gardasil, the quadrivalent HPV vaccine made by Merck that is more widely used in the United States and many other countries.

More research is needed before any formal changes can be decided, but Safaeian said the findings could have far-reaching impact in low income nations.

"Vaccination with two doses, or even one dose, could simplify the logistics and reduce the cost of vaccination, which could be especially important in the developing world, where more than 85 percent of cervical cancers occur, and where cervical cancer is one of the most common causes of cancer-related deaths," she said.

HPV can cause oral, anal, and cervical cancer.

According to the World Health Organization, cervical cancer is the second most common cancer in women worldwide, and causes 500,000 new cases and 250,000 deaths each year.

Source: AFP
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Printed Temperature Sensors help with Continuous Temperature Monitoring
Health Benefits of Giloy
Breast Cancer Awareness Month 2021 - It's time to RISE
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Women and Cancer Cancer and Homeopathy Cervical Cancer Cancer Facts Cancer Tattoos A Body Art Uterine Cancer AIDS-HIV-Cancer Anal Warts Health Screening for Women 

Recommended Reading
Cervical Cancer - Incidence
Cervical cancer is the second most common cancer among women and is the primary cause of ......
Pap smear and Cervical Cancer Screening
Pap smear is the most common test used in screening cervical cancer caused by an infection with ......
Women and Cancer
Cancer is one of the frequently talked about and most feared disease that falls under the genre of ....
AIDS-HIV-Cancer
AIDS defining malignancies are cancers that occur in patients with AIDS due to their low immunity....
Anal Warts
Anal warts or genital warts are soft bumps caused by Human Papilloma Virus and are a sexually transm...
Cervical Cancer
Cancer cervix refers to cancerous growth in the cervix and usually occurs in the transition called ...
Health Screening for Women
Health screening in women between 40 and 60 years helps to diagnose health issues in the early stage...
Tattoos A Body Art
Tattoos are a rage among college students who sport it for the ‘cool dude’ or ‘cool babe’ look...
Uterine Cancer
Uterine Cancer or Cancer of the Uterus (or Endometrial Cancer) refer to cancers affecting the uterus...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use