The use of iodinated contrast material may be less damaging to the kidneys than previously recorded, according to a recent study conducted by researchers at Columbia University Medical Center in New York.
"We reviewed patient records to determine the frequency and magnitude of serum creatinine changes in patients who had not received iodinated contrast material. We then compared that to previously published articles which found a relationship between contrast media, serum creatinine levels and nephropathy (kidney damage).
"We found that the creatinine level increases just as often in those who do not receive contrast material as in those who do," said Jeffrey Newhouse, MD, lead author of the study.
"Because serum creatinine levels change frequently in the absence of iodinated contrast media material, prior studies of the relationship between iodinated contrast material and renal function must be interpreted with caution, and future experiments should have appropriate controls," Dr. Newhouse said. "We don't claim that IV contrast material never induces nephropathy, but it may do so less frequently and severely than previously thought.
If subsequent experimentation proves its safety, it could be used more frequently in patients with renal failure," he said.