Bengaluru-based biotech firm, Pandorum Technologies, has announced that it has developed artificial living tissue using 3D printing which performs the function of a human liver. These 3D printed tissues can lead to affordable, full-scale transplantable organs in few years.
"Development of artificial organs has numerous clinical uses. Cell-based organoids can be used to develop bio-artificial liver support systems for preserving life in patients who have developed liver failure. In the near future, such bio-printed organs will address the acute shortage of human organs available for surgical transplantation," said Bhowmick, co-founder of Pandorum.
‘Pandorum Technologies has developed 3D printed liver tissues that would help revolutionize organ donation and transplantation in India.’
Pandorum is the first Indian company to develop artificial living tissues which can be kept alive for four weeks. Pandorum is funded by the Department of Biotechnology and incubated at the Center for Cellular and Molecular Platforms (C-CAMP), Bangalore Bio-Cluster.
"Liver toxicity and drug metabolism are the key hurdles, and contributors to failed human trials. Our 3D bio-printed mini-livers that mimic the human liver will serve as test platforms for discovery and development of drugs with better efficacy, less side-effects and at lower costs," said Arun Chandru, co-founder and managing director of Pandorum.
"We are able to print around 10 million cells currently. By 2020, we will increase our efficiency to printing one billion cells. It is only by 2030 that we will be equipped to print 100 billion cells, and it is then when we envisage to print on-demand organs for full-scale transplantation," added Arun Chandru.