About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

In COPD Patients, Inflammation Is Associated With Depression

by Bidita Debnath on May 25, 2013 at 11:48 PM
Font : A-A+

 In COPD Patients, Inflammation Is Associated With Depression

In chronic obstructive pulmonary disease (COPD) patients, depression is common and has been linked with disease severity and impaired quality of life.

Now, for the first time, researchers at the University of Pittsburgh have linked the systemic inflammation associated with COPD with depression in these patients.

Advertisement

"Systemic inflammation is thought to be an important mediator of comorbidities in COPD, but the relationship between inflammation and depression has not been explored," said researcher Hilary Strollo, M.S., a graduate of the University of Pittsburgh School of Health and Rehabilitation Sciences. "In our study, we found a strong association between depressive symptoms and levels of the inflammatory biomarker interleukin-6 (IL-6) which was independent of the severity of airflow obstruction."

The study results will be presented at the ATS 2013 International Conference in Philadelphia.

The study included 450 tobacco-exposed patients. Assessment included the Beck Depression Inventory (BDI), the Saint George Respiratory Questionnaire (SGRQ), and the UCSD Shortness of Breath Questionnaire (SOBQ). Spirometry and multi-detector computed tomography (MDCT) of the chest were also performed.
Advertisement

Of 235 male patients enrolled, 37 were depressed, and of 215 females, 49 were depressed. Clinical and biological variables that were found to be significantly associated with depression included the forced expiratory volume or FEV1, a measure of the maximum amount of air that can be exhaled in one second, gender, IL-6 levels, SGRQ Total Score, UCSD SOBQ Total Score, Visual Emphysema Score, and current smoking status.

The strongest associations were seen between depressive symptoms and FEV1, followed by female gender, current smoking status and increased IL-6.

"Depression has been linked with a number of symptoms and comorbidities in COPD patients," said Ms. Strollo. "Our findings add evidence of a strong relationship between depression and one of the hallmarks of COPD, systemic inflammation, independent of the severity of disease."

"The assessment and treatment of depression should be part of the routine care of COPD patients."

Source: Newswise
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
News Category
What's New on Medindia
International Day of Persons with Disabilities 2021 - Fighting for Rights in the Post-COVID Era
Effect of Blood Group Type on COVID-19 Risk and Severity
Woman with Rare Spinal Cord Defect from Birth Sues Doctor
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Adolescence Depression Depression Stress Relief Through Alternative Medicine Andropause / Male Menopause Pregnancy and Complications Pneumoconiosis Pulmonary Arterial Hypertension Holistic Management for Depression Tourette Syndrome Dealing with Menopause symptoms through lifestyle changes 

Recommended Reading
Chronic Obstructive Pulmonary Disease
COPD includes respiratory tract disorders that cause obstruction to airflow. These are chronic .....
Extended Use of Common Antibiotics may Cut Down on Hospitalization Rates Among COPD Patients
A comparison study reveals that extended used of antibiotics may prolong the time between ......
COPD Is Associated With Significant and Persistent Pain: Study
Chronic obstructive pulmonary disease (COPD) is primarily associated with the respiratory symptoms ....
Measuring Exercise Levels can Predict Hospitalization Risk Among COPD Patients
A new study suggests that measuring exercise levels of patients with COPD can predict whether or ......
Andropause / Male Menopause
Andropause or male menopause causing low libido in a man is due to decreasing level of male hormones...
Dealing with Menopause symptoms through lifestyle changes
You can deal with menopause symptoms such as hot flashes, weight gain and forgetfulness by making si...
Depression
Depression is one of the most common mental disorders affecting approximately 340 million people in ...
Holistic Management for Depression
Depression is a common disorder and many worldwide suffer from depression. Early recognition of symp...
Pneumoconiosis
Pneumoconiosis is a group of lung diseases caused by inhaled dust particles. It causes inflammation ...
Pregnancy and Complications
In-depth guide for expecting mothers to overcome health complications related to early or late pregn...
Pulmonary Arterial Hypertension
It can be a serious condition affecting the heart. It is defined as mean pulmonary arterial pressure...
Tourette Syndrome
Tourette syndrome (TS) is a neurological disorder wherein the affected person makes repetitive and s...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use