They found that pure resveratrol intake was associated with higher lung volumes and that white wine intake (but not red wine intake) and was associated with lower risk of airway obstruction. They also report that the genetic factors studied did not relate to the associations found.
While several previous studies have reported that wine intake improves lung function, Forum reviewers were concerned about several aspects of the paper, and especially with the conclusions of the authors that resveratrol was the key factor in improved lung function.
"Resveratrol may well be just the bystander of something else present in wine," a reviewer said.
"The beneficial effects on lung function are probably related to many compounds present in wine, and not just resveratrol," the reviewer said.
Based on a number of scientific studies, moderate wine intake appears to have a favourable effect on lung function.
The doses of resveratrol seen in these epidemiologic studies are at levels that could be expected from moderate wine consumption, unlike the huge doses of resveratrol, which may not be capable of being metabolized, being evaluated as a potential life-extending drug in pharmaceutical studies.