Antioxidant nutrients, foods high in carotenoids, fruits, and vegetable intake appear to be associated with better amyotrophic lateral sclerosis (ALS) function at baseline, according to the results of a new article published in JAMA Neurology.
A study of ALS progression was used to examine associations between nutritional intake, function and respiratory function at the time of study entry for patients who had ALS symptoms for 18 months or less.
There is interest in the potential role of nutrition and environmental factors in the pathogenesis (development) of ALS and in disease progression.
The analysis relied on nutrient intake reported using a food questionnaire; rating scores were used to measure function; and respiratory function was measured using the percentage of predicted force vital capacity (FVC). Higher rating scores and a higher percentage of FVC indicated better function.
Antioxidant nutrients, foods high in carotenoids, fruits, and vegetable intake appear to be associated with better ALS function at baseline, according to the results.
Authors note their study results cannot establish cause and effect. Also, the study relied on a food questionnaire and those may not always represent a true daily diet. "Those responsible for nutritional care of the patient with ALS should consider promoting fruit and vegetable intake since they are high in antioxidants and carotenes," the study concludes.