Medindia
Advertisement

Phase III Trial of New Immune Therapy Drug shows Promise Against Multiple Myeloma

by Dr. Trupti Shirole on May 15, 2015 at 7:25 AM

Phase III Trial of New Immune Therapy Drug shows Promise Against Multiple Myeloma
Immunotherapy or immune therapy is a treatment that uses the body's own immune system to help fight cancer. A new kind of immunotherapy has shown promise against the third most common blood cancer, multiple myeloma. The drug, elotuzumab, is a monoclonal antibody, a type of immune protein, made by Bristol Myers-Squibb, and was granted a breakthrough therapy designation by the US Food and Drug Administration last year.

The phase III clinical trial involved 646 people who had multiple myeloma which recurred after initial treatment with the standard therapy, lenalidomide and dexamethasone. Study participants were randomly assigned to receive either the standard therapy, or the standard therapy plus elotuzumab. After a follow-up period of about two years, patients who took the additional drug saw a 30% lower risk of dying or having their cancer return, compared to the other group. Study participants in the elotuzumab group also lived an average of 19.4 months without their disease getting worse, compared to 14.5 months on the standard arm, a difference that researchers described as 'significant'.
Advertisement

Sagar Lonial, chief medical officer of the Winship Cancer Institute at Emory University, said, "The longer remission and higher overall response rate in the elotuzumab group came without a big increase in adverse effects and no reduction in quality of life. The drug works by targeting both the tumor cells and enhancing the activation of natural killer cells in the immune system. In many ways it is a bit of a double whammy, if you will, in terms of the tumor itself."

The study was released ahead of the American Society of Clinical Oncology conference, to be held later this month in Chicago.

Source: Medindia
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Stroop Effect
Plant-Based Diet may Reduce the Risk of COVID-19
Lower Respiratory Tract Infections Linked to Obstructive Sleep Apnea in Children
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Drug Toxicity Reiki and Pranic Healing Signature Drug Toxicity Multiple Myeloma Myasthenia Gravis Placebo Effects: Rare Insights Cancer Immunotherapy 

Recommended Reading
New Ways To Treat Blood Cancers Revealed
The blood cancer charity Leukemia and Lymphoma Research has awarded 115,000-pounds to the ......
Aging Gene Linked to Blood Cancer
A major new study suggests that a gene that helps control the ageing process by acting as a cell's ....
African-Americans With Blood Cancer Tend to Have Shorter Survival Times
Among patients with chronic lymphocytic leukemia, African Americans more commonly present with ......
Cancer Immunotherapy
Cancer immunotherapy is a new advancement in cancer treatment that uses certain components of a pers...
Drug Toxicity
Drug toxicity is an adverse reaction of the body towards a drug that results as a side effect of a d...
Multiple Myeloma
Multiple Myeloma caught public attention when model turned actress Lisa Ray, who worked in Deepa Meh...
Myasthenia Gravis
Myasthenia gravis is the commonest disorder of neuromuscular transmission. Autoimmune myasthenia gra...
Placebo Effects: Rare Insights
Placebo response is now generally well accepted. ‘Placebo response’ is the friend of the clinician a...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use