About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Identify Asthma Types with Common Biological Features

by Preethi Sivaswaamy Mohana on March 15, 2018 at 12:43 PM
Font : A-A+

Identify Asthma Types with Common Biological Features

People with mild asthma can be identified from those with moderate or severe asthma using the identified biological variations in lung tissue samples, according to a study by a team of researchers from the NIHR Leicester Biomedical Research Centre - a partnership between Leicester's Hospitals, the University of Leicester and Loughborough University. The findings of the study are published in the Journal of Allergy and Clinical Immunology.

The team led by Professors Salman Siddiqui and Peter Bradding used state-of-the-art statistical methods involving visualisation approaches, to perform the largest comprehensive analysis of common pathological features in the airways of people with Asthma of different severities. They also investigated the clinical features of these subtypes and whether there is any association with changes in genes and decline in lung function.

Advertisement


Professor Siddiqui and his team identified multiple biological 'micro-clusters' which means that there are different combinations of active genes in each of the reported subtypes of Asthma .

Professor Bradding, who is a Professor of Respiratory Medicine at the University of Leicester and Consultant Respiratory Physician at Leicester's Hospitals, said: "The most exciting thing about finding these biological variations underpinning the differences between mild asthma and moderate and severe asthma is that the statistical methods if further developed could lead to the development of new, targeted treatments for subtypes of asthma, thus allowing the right Asthma to be matched to different patients. In this scenario, patients would benefit because they would be offered more personalised, and therefore more effective, care to manage their asthma."
Advertisement

Professor Siddiqui, Professor of Airway Diseases at the University of Leicester and Consultant Respiratory Physician at Leicester's Hospitals, added: "Further research is now underway to understand how to use these statistical approaches to combine complex information in asthma patients and make personalised treatment decisions."

Dr Samantha Walker, Director of Research and Policy at Asthma UK, which funded the study, said: "For a long time, asthma has been considered as one condition, but this research illustrates the growing understanding that the term 'asthma' is in fact an umbrella term for different lung conditions. There needs to be a much better understanding of how to identify different types of asthma so that treatment can be tailored to prevent asthma attacks and keep people out of hospital. We are calling for more research into asthma, particularly into improving and developing diagnostic tools so that people can be diagnosed and treated quickly and effectively."



Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
News Category
What's New on Medindia
International Day of Persons with Disabilities 2021 - Fighting for Rights in the Post-COVID Era
Effect of Blood Group Type on COVID-19 Risk and Severity
Woman with Rare Spinal Cord Defect from Birth Sues Doctor
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Childhood Asthma Asthma Remedies for Seasonal Allergy Relief Allergy - Symptom Evaluation Wheezing Churg-Strauss Syndrome Tests for Asthma Stay Well This Winter Occupational Asthma 

Recommended Reading
Asthma
It's a lung condition characterized by inflammation of the bronchi and constriction of the airways ....
Asthma Patients Could Find Relief with New Drug Therapy
Novel drug that opens the lungs' airways - an effective treatment for asthma patients...
Asthma Biomarkers from Lung Bacteria Identified
The lung microbiome plays a key role in asthma severity and response to treatment. Microbiome is a ....
Asthma Patients are Benefited by Asthma APGAR Tools
The Asthma APGAR tools are effective for asthma management by reducing the patient's visit to ......
Allergy - Symptom Evaluation
An allergic reaction may be mild or severe. It usually involves the skin, respiratory system, eyes,...
Childhood Asthma
Childhood asthma is a condition that affects airways in children and interferes with their daily act...
Churg-Strauss Syndrome
Churg-Strauss Syndrome is a rare disease characterized by inflammation of blood vessels that can res...
Occupational Asthma
Occupational Asthma (OA) is a lung disorder that occurs due to exposure to toxic substances at the w...
Remedies for Seasonal Allergy Relief
Understanding the cause and mechanism of seasonal allergy can help in choosing the right treatment. ...
Stay Well This Winter
Winter is associated with staying huddled indoors, people scurrying home to escape the piercing wint...
Tests for Asthma
Do you find it difficult to breathe especially during the cold weather? You may need to get tested f...
Wheezing
Wheezing is a sound arising from the airways due to an obstruction or narrowing, which prevents the ...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use