About Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

HPV Vaccine Could Protect Women from Breast Cancer

by VR Sreeraman on September 6, 2009 at 12:22 PM
Font : A-A+

 HPV Vaccine Could Protect Women from Breast Cancer

Human papillomavirus (HPV) vaccine can prevent some forms of breast cancer in women and save thousands of lives each year, suggested an Australian study.

Researchers at the University of New South Wales used genetic probes to test cancerous breast cells, and found several strains of HPVs, which are known to have a high risk of initiating cancer of the cervix.

Advertisement

HPV has a causal role in 90-95 per cent of cervical cancers.

Led by Visiting Professor James Lawson at UNSW, the researchers confirmed the presence of high-risk HPV in the nuclei of breast cancer epithelial cells in five (39 per cent) of 13 ductal carcinoma in situ and three (21 per cent) of 14 invasive ductal carcinoma (IDC) breast cancer specimens.
Advertisement

Non-invasive or in situ cancers are those confined to the milk-making glands, and do not spread to other parts of the breast or body.

Invasive cancers such as IDC are more serious and account for 70-80 percent of all breast cancers.

"The finding that high risk HPV is present in a significant number of breast cancers indicates they may have a causal role in many breast cancers. Confirming a cancer-causing role for HPV in some breast cancers establishes the possibility of preventing some breast cancers by vaccination against HPV," said Dr Noel Whitaker, a co-author of the new report.

HPVs involvement in breast cancer has long been a topic of controversy, as studies from 15 countries around the world have identified the presence of high-risk types of HPV in breast tissue and breast cancer specimens.

However, those studies have also showed widely varying results, with the prevalence of HPV-positive breast cancer in ranging from as low as four per cent to as high as 86 per cent, and have been clouded by difficulties in detecting the virus in breast specimens.

Besides, the genetic probe technique used - polymerase chain reaction (PCR) - has been criticized for its propensity for contamination.

The technique is based on taking small genetic samples and rapidly copying them to provide a large enough sample to study.

The researchers in the new study have dealt with these issues by using a technique (in situ PCR) that avoids cross-contamination and that provides evidence about whether HPV genetic material is present in the nuclei of human breast cancer specimens.

They validated their findings by looking for "telltale" changes linked to HPV such as enlarged nucleus surrounded by a characteristic "halo".

Now, the researchers are working on a new method that will make testing even quicker, cheaper and simpler.

The study has been published in the British Journal of Cancer.

Source: ANI
SRM
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
Monkeypox Outbreak: What it is, How Does it Spread & the Prevention
Seasonal Allergy Medications
How to Choose the Best Eczema-Friendly Moisturizer for Children?
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Women and Cancer Pagets disease of the breast Mastitis Cancer and Homeopathy Cervical Cancer Breast Cancer Facts Cancer Facts Cancer Tattoos A Body Art Breasts - Structures and Types 

Most Popular on Medindia

Color Blindness Calculator Hearing Loss Calculator Blood Pressure Calculator Blood Donation - Recipients Noscaphene (Noscapine) A-Z Drug Brands in India Pregnancy Confirmation Calculator Nutam (400mg) (Piracetam) Drug Side Effects Calculator How to Reduce School Bag Weight - Simple Tips

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2022

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use