Understanding the role of protein synthesis during cell division will shed light on when cells will initiate their division, how fast they will complete it.
Protein P53 Prevents Cell Division When the Right Machinery is Not in Place
New tools for centriole manipulation should help researchers figure out how p53 helps safeguard cells - and how it has the potential to cause cancers.
New tools for centriole manipulation should help researchers figure out how p53 helps safeguard cells - and how it has the potential to cause cancers.
‘The enzymes that make lipids and membranes were synthesized at much greater efficiency when a cell is ready to split.’
Microscopy images of dividing yeast cells accumulating lipid
droplets (shown as bright spots) because they have lost their ability to
regulate the synthesis of a key lipogenic enzyme. Polymenis said the finding provides new targets for controlling cell division in future studies.
"Understanding the role of protein synthesis during cell division will shed light on when cells will initiate their division, how fast they will complete it, the number of successive cell divisions, and the coordination of cell proliferation with the available nutrients," said Dr. Heidi Blank, Texas A&M University assistant scientist and the paper's co-author.
Study Finds Link Between Cell Division, Glucose and Insulin
Three spindle checkpoint proteins long associated with the timing of cell division are central to the newly identified mechanism that regulates insulin signaling.
Three spindle checkpoint proteins long associated with the timing of cell division are central to the newly identified mechanism that regulates insulin signaling.
The report, which included scientists from Texas A&M and The Buck Institute for Research on Aging, noted that no studies previously had "queried directly and comprehensively the efficiency with which each individual protein is made during cell division in growing cells."
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Inhibiting Enzymes in the Cell may Prevent Cancer Cell Division and Growth
According to researchers at the Graduate School of Biomedical Sciences at the Icahn School of Medicine at Mount Sinai, blocking certain enzymes in the cell may prevent cancer cell division and growth.
According to researchers at the Graduate School of Biomedical Sciences at the Icahn School of Medicine at Mount Sinai, blocking certain enzymes in the cell may prevent cancer cell division and growth.
"If the dream of every cell is to become two cells as the Nobelist François Jacob famously quipped in 1971, then it is protein synthesis that makes cellular dreams come true," he said. "Protein synthesis underpins much of cell growth and determines the rate at which cells proliferate."
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Cell Division Controlling Molecular Tag Revealed
Three protein complexes act in relay to regulate cell division, the reactivation of one leads to the second cell becoming active. This information is found in a ground-breaking paper published.
Three protein complexes act in relay to regulate cell division, the reactivation of one leads to the second cell becoming active. This information is found in a ground-breaking paper published.
Source-Eurekalert
