About Careers Internship MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

How Does Your Stomach Tell Your Brain That You are Full?

by Reshma Anand on November 26, 2015 at 5:22 PM
Font : A-A+

How Does Your Stomach Tell Your Brain That You are Full?

The importance of gut microbes has been growing recently due to its extensive association with the key pathways of the human body. It's role in metabolism is a well-known factor, but do you know it can also regulate the amount of food consumption.

In a recent study published in the Journal Cell Metabolism researchers have reported that gut microbes send signals to the brain once it is full. This signal can play a very important role in determining the amount of food consumed by a person.

Advertisement


Humans have about 70% of microbes in their colon. Gut microbes especially E.coli play a very important role in digestion. A team of researchers led by Dr. Serguei Fetissova at the Rouen University in France analyzed samples of protein produced by E.coli before and after a meal.

Researchers found that after a period of 20 minutes when a person eats, E.coli bacteria started to produce a set of proteins which triggered a hormone to send signals to the brain for food termination.
Advertisement

The protein samples were tested on mice before and after a meal. After the mice were fed for a period of 20 minutes, the scientists induced this protein into the mice which immediately triggered a hormone to send signals for the mice to stop eating.

They found that the E.coli bacteria triggered the production of the post-meal hormones GLP-1 and PYY. ClpB, a bacterial protein mimetic of α-MSH, was upregulated in the E. coli stationary phase. This influence the host to stop eating and also determines the host satiety.

"We will continue to look into the mechanism of how that bacteria can regulate appetite, particularly in people who are obese or who suffer from binge-eating disorders. And if we find some involvement, I hope we can also treat these conditions." Fetissov said.

Reference:Sergue´ O. Fetissov, Jonathan Breton, et al. "Gut Commensal E. coli Proteins Activate Host Satiety Pathways following Nutrient-Induced Bacterial Growth," Journal Cell Metabolism, published on November 24, 2015, http://dx.doi.org/10.1016/j.cmet.2015.10.017

Source: Medindia
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
Anemia among Indian Women and Children Remains a Cause of Concern- National Family Health Survey-5
H1N1 Influenza Prevention in Children: What Parents Need to Know
Dietary Factors Responsible for Dihydrotestosterone (DHT) Production and Hair Loss
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Parkinsons Disease Parkinsons Disease Surgical Treatment Brain Brain Facts Ataxia Language Areas in The Brain Ways to Improve your Intelligence Quotient (IQ) COX - 2 Inhibitors 

Most Popular on Medindia

Vent Forte (Theophylline) Turmeric Powder - Health Benefits, Uses & Side Effects Noscaphene (Noscapine) Drug Interaction Checker Iron Intake Calculator Find a Doctor Calculate Ideal Weight for Infants Hearing Loss Calculator Accident and Trauma Care Blood - Sugar Chart
This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use
×

How Does Your Stomach Tell Your Brain That You are Full? Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests