About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Higher BMI Increases Risk of Dementia

by Hannah Joy on December 1, 2017 at 5:19 PM
Font : A-A+

Higher BMI Increases Risk of Dementia

Overweight or obese individuals who have higher body mass index (BMI) are at greater risk of developing dementia when compared to those with normal weight, revealed a new UCL-led study.

The study, published in the Alzheimer's & Dementia journal, analysed data from 1.3 million adults living in the United States and Europe.

Advertisement


The researchers also found that people near dementia onset, who then go on to develop dementia, tend to have lower body weight than their dementia-free counterparts.

"The BMI-dementia association observed in longitudinal population studies, such as ours, is actually attributable to two processes," said lead author of the study, Professor Mika Kivimäki (UCL Institute of Epidemiology & Health).
Advertisement

"One is an adverse effect of excess body fat on dementia risk. The other is weight loss due to pre-clinical dementia. For this reason, people who develop dementia may have a higher-than-average body mass index some 20 years before dementia onset, but close to overt dementia have a lower BMI than those who remain healthy."

"The new study confirms both the adverse effect of obesity as well as weight loss caused by metabolic changes during the pre-dementia stage."

Past research on how a person's weight influences their risk of dementia has produced conflicting results. Some findings have suggested that being obese poses a higher dementia risk, but other studies have linked lower weight to increased dementia incidence.

In this study, researchers from across Europe pooled individual-level data from 39 longitudinal population studies from the United States, the United Kingdom, France, Sweden, and Finland.

A total of 1,349,857 dementia-free adults participated in these studies and their weight and height were assessed. Dementia was ascertained using linkage to electronic health records obtained from hospitalisation, prescribed medication and death registries.

A total of 6,894 participants developed dementia during up to 38 years of follow-up. Two decades before symptomatic dementia, higher BMI predicted dementia occurrence: each 5-unit increase in BMI was associated with a 16-33% higher risk of this condition (5 BMI units is 14.5kg for a person 5'7" (170cm) tall, approximately the difference in weight between the overweight and normal weight categories or between the obese and overweight categories).

In contrast, the mean level of BMI during pre-clinical stage close to dementia onset was lower compared to that in participants who remained healthy.

In 2015, the number of people with dementia reached almost 45 million, two times more than in 1990. This study suggests that maintaining a healthy weight could prevent, or at least delay, dementia.



Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
News Category
What's New on Medindia
International Day of Persons with Disabilities 2021 - Fighting for Rights in the Post-COVID Era
Effect of Blood Group Type on COVID-19 Risk and Severity
Woman with Rare Spinal Cord Defect from Birth Sues Doctor
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Alzheimers Disease Bulimia Nervosa BMI Ideal Body Weight Body Mass Index Exercise To Gain Weight Mantra to Prevent Childhood Obesity – Vigorous Physical Activity Malnutrition to Obesity - The Big Leap Quiz on Weight Loss Dementia 

Recommended Reading
Body Mass Index
Body mass index (BMI) is a simple tool that is generally used to estimate the total amount of body ....
Gestational diabetes
The condition is not caused by a lack of insulin, but by the action of hormones produced during ......
Obesity during Pregnancy: Know the Risks
Women with a body mass index >30 are obese and are at a higher risk for gestational diabetes during ...
Alzheimers Disease
Alzheimer's disease is a progressive neurodegenerative disease affecting memory and thinking and mak...
Bulimia Nervosa
The term ''Bulimia'' refers to episodes of uncontrolled excessive eating, known as "binges," followe...
Dementia
Dementia has become a very big concern as we have an aging population across the world. Dementia is ...
Exercise To Gain Weight
Are you underweight and want to know how to gain weight? Exercise or workouts can help you gain weig...
Ideal Body Weight
India and China, which are epicenters of a booming economy, are now witnessing a steady rise in obes...
Malnutrition to Obesity - The Big Leap
Obesity is the root cause of problems like diabetes, heart disease, stroke, arthritis and gall bladd...
Mantra to Prevent Childhood Obesity – Vigorous Physical Activity
Being physically very active is the mantra to prevent pediatric obesity rather than concentrating ef...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use