About Careers MedBlog Contact us

High-Risk Breast Cancer Result of African Heritage

by Rathi Manohar on July 24, 2010 at 1:44 PM
Font : A-A+

High-Risk Breast Cancer Result of African Heritage

Triple-negative breast cancer, a hard-to-treat type of cancer, is connected to African ancestry, states a new study.

Triple negative breast cancer is negative for three specific markers that are used to determine treatment: the estrogen receptor, the progesterone receptor and HER-2/neu.


But these treatments do not help women with triple-negative breast cancer. Outcome disparities are therefore likely to increase, because fewer African-American women are candidates for these newer treatments," says study author Lisa A. Newman, M.D., M.P.H., director of the Breast Care Center at the U-M Comprehensive Cancer Center.

Researchers found that Ghanaian women were diagnosed at a younger age than American women, and with larger tumours and more advanced cancer.

Ghanaian women were also more likely to test negative for each of the three markers.

"African ancestry might be associated with other links to hereditary predisposition for particular patterns of breast cancer.

We hope that by studying breast cancer in African and African-American women we can identify biomarkers that might be useful for assessing risk or treating triple-negative breast cancer," says Newman, professor of surgery at the U-M Medical School.

The study, published online in the journal Cancer.

Source: ANI

Recommended Reading

This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close

High-Risk Breast Cancer Result of African Heritage Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests