About Careers MedBlog Contact us

High Dose Influenza Vaccine Improves Immunity in Elderly

by VR Sreeraman on October 28, 2008 at 11:22 AM
Font : A-A+

 High Dose Influenza Vaccine Improves Immunity in Elderly

A high dose of influenza vaccine helps protect the elderly better than the standard vaccine, say researchers.

Researchers at the University of Rochester School of Medicine in New York found that a high dose of potential drug candidate under trail increased immune responses among adults 65 years of age and older, compared with the standard influenza vaccine.


The candidate high-dose intramuscular formulation of the influenza vaccine is being developed by sanofi pasteur.

Older adults become not only more susceptible to infections, but also less responsive to vaccination.

"Development of an influenza vaccine that will provide an improved immune response in older adults is important because this population has the highest rates of complications from influenza including hospitalization and death," said Dr Ann R. Falsey, Associate Professor of Medicine.

According to the U.S. Centres for Disease Control and Prevention (CDC), the currently available inactivated influenza vaccine offers public health benefits in reducing influenza-related morbidity and mortality in older adults.

During the study, the 4000 people 65 years of age and older compared the high-dose influenza vaccine with the standard inactivated influenza vaccine formulated for the 2006-2007 season.

They found that that the new high-dose vaccine increased the immune responses to all three influenza strains compared with standard vaccine.

The results were reported at the 48th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC)/Infectious Diseases Society of America (IDSA) 46th annual meeting.

Source: ANI


Recommended Reading

Latest Senior Health News

Walking: The Route to Delaying Alzheimer's Disease
Regular walking can delay Alzheimer's disease by strengthening the links in and between brain networks, according to a recent study.
 Calorie Restriction Prevents Age-Related Memory Loss
New study evaluated the effects of calorie restriction on memory in aged male Wistar rats, as well as those on brain structure changes, neurogenesis, and inflammation.
Why Do Prescription Opioids Impact Cognitive Function in Older Adults?
Seniors who received opioids over an average of 7.5 years were found to experience 20% increased chance of developing cognitive impairment.
How Does Parathyroidectomy Affect Kidney Function in Older Adults?
Physicians must discuss the probable benefit of early parathyroidectomy to decrease kidney disease risk and related complications.
 Phototherapy May Enhance Cognitive Function in Dementia
Phototherapy or exposure to bright light therapy may be one of the most promising non-pharmacological interventions that improve dementia symptoms.
View All
This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close

High Dose Influenza Vaccine Improves Immunity in Elderly Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests