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High BP During Pregnancy can Likely Cause Autism in Children

Being born to women who suffer a high-blood pressure condition called pre-eclampsia during pregnancy, the children are twice likely to have autism.

 High BP During Pregnancy can Likely Cause Autism in Children
Being born to women who suffer a high-blood pressure condition called pre-eclampsia during pregnancy, the children are twice likely to have autism or other developmental delays, say US researchers. The study in the journal JAMA Pediatrics, a journal of the American Medical Association, also found that the more severe the pre-eclampsia, the higher the likelihood of autism.
The study in the journal JAMA Pediatrics, a journal of the American Medical Association, also found that the more severe the pre-eclampsia, the higher the likelihood of autism.

The research involved more than 1,000 children aged two to three in northern California. All of their mothers had confirmed diagnoses of pre-eclampsia, and scientists compared data about those developing normally to those with autism spectrum disorder (ASD) or other developmental delays.

"We found significant associations between pre-eclampsia and ASD that increased with severity," said senior author Cheryl Walker, assistant professor in the department of obstetrics and gynecology at the University of California, Davis.

"We also observed a significant association between severe pre-eclampsia and developmental delay."

Autism spectrum disorder affects as many as 1 in 88 children in the United States.

The exact causes of the developmental disorder are unknown, with research pointing to genes, the environment, or both.

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Autism leads to difficulties in social, emotional and communication skills, and has no known cure.

Some past research has suggested that pre-eclampsia -- which causes high blood pressure late in pregnancy and high levels of protein in the urine, as well as seizures in severe cases -- could be linked to autism, perhaps by depriving the fetus of nutrients and oxygen.

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"While single studies cannot establish causality, the cumulative evidence supports efforts to reduce pre-eclampsia and diminish severity, to improve neonatal outcomes," Walker said.

Source-AFP


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