High adherence to antiretroviral pre-exposure prophylaxis (PrEP) is associated with a high level of protection from HIV acquisition by HIV-uninfected partners in heterosexual couples where only one of the partners is HIV positive.
This is according to a study published in this week's PLOS Medicine. The study, which was led by Jessica Haberer, from Harvard Medical School, Boston, United States, included 1,147 HIV-uninfected participants who were enrolled in three Ugandan sites of the Partners PrEP Study- a randomized controlled trial to determine efficacy and safety of PrEP. All participants had a partner who was HIV-positive. These participants were a convenience sample reflecting 66% of all participants in the study sites (they were not randomized as part of this substudy). They were actively monitored for adherence to antiretroviral drugs and received adherence counselling throughout the study, which was intensified if unannounced pill count adherence fell below 80%.
Research: Translating Nature's Library Yields Drug Lead for AIDS
A scientist has said that an ingredient in a medicinal tea brewed from tree bark by tribal healers on the South Pacific island of Samoa is showing significant promise.
A scientist has said that an ingredient in a medicinal tea brewed from tree bark by tribal healers on the South Pacific island of Samoa is showing significant promise.
Although the study has some limitations, such as the non-randomized nature of the study and limitations inherent in any form of adherence monitoring, the findings indicate that the high level of PrEP adherence achieved in the setting of active adherence monitoring and counselling support was associated with a high level of protection from HIV acquisition by the HIV-uninfected partner in heterosexual serodiscordant couples.
The authors note, "These data provide further support that PrEP is highly efficacious at preventing HIV acquisition when it is taken."
330,000 New Pediatric Infections Added To Pool Of 3.4 Million Children Living With AIDS
The scope of the current HIV elimination agenda must be broadened in order to ensure access to care and treatment for all children living with HIV argues Scott Kellerman and colleagues.
The scope of the current HIV elimination agenda must be broadened in order to ensure access to care and treatment for all children living with HIV argues Scott Kellerman and colleagues.
Source-Eurekalert
Early Use of Antiretroviral Drugs Helps Children Fight AIDS
Doctors reported that a landmark five-year trial has strengthened evidence that early use of antiretroviral drugs helps children combat the AIDS virus.
Doctors reported that a landmark five-year trial has strengthened evidence that early use of antiretroviral drugs helps children combat the AIDS virus.
HIV/AIDS Burden Shifts to Changing Group of Regions
Showing that greater attention and financial investment may be needed in places where the disease has not reached epidemic levels, the HIV/AIDS epidemic is changing in unexpected ways in countries around the world.
Showing that greater attention and financial investment may be needed in places where the disease has not reached epidemic levels, the HIV/AIDS epidemic is changing in unexpected ways in countries around the world.
